Eosinophilic Gastroenteritis (EG) is a rare chronic inflammatory disorder that affects the gastrointestinal tract. It is characterized by an excessive accumulation of eosinophils, a type of white blood cell, in the lining of the stomach, small intestine, and/or large intestine.
EG can present with a variety of symptoms depending on the affected area of the gastrointestinal tract. Common symptoms include abdominal pain, nausea, vomiting, diarrhea, bloating, and weight loss. In severe cases, it can lead to malnutrition and growth impairment, particularly in children.
The exact cause of EG is unknown, but it is believed to be related to an abnormal immune response to certain foods or environmental triggers. Allergies, autoimmune disorders, and genetic factors may also play a role. Diagnosis typically involves a combination of medical history, physical examination, blood tests, endoscopy, and biopsy.
Treatment for EG aims to reduce inflammation and manage symptoms. This may involve dietary changes, such as eliminating specific food triggers, and medications to suppress the immune response, such as corticosteroids or immunomodulators. In some cases, surgical intervention may be necessary.
EG is a chronic condition that requires long-term management and regular monitoring. With appropriate treatment, most individuals with EG can achieve symptom control and lead a normal life.