What is Multiple Endocrine Neoplasia

Multiple Endocrine Neoplasia (MEN) is a rare genetic disorder that affects the endocrine system, which is responsible for producing hormones in the body. It is characterized by the development of tumors, or neoplasms, in multiple endocrine glands.

There are several types of MEN, including MEN1, MEN2A, and MEN2B, each associated with specific gene mutations. MEN1 primarily affects the parathyroid glands, pituitary gland, and pancreas, leading to overproduction of hormones and subsequent health issues. MEN2A and MEN2B primarily affect the thyroid gland, adrenal glands, and other organs, causing the development of tumors and hormonal imbalances.

Due to its genetic nature, MEN can be inherited from affected parents. Symptoms may vary depending on the specific type and organs involved, but commonly include hormonal imbalances, growth abnormalities, and the presence of tumors. Early diagnosis and regular screenings are crucial for managing MEN and preventing complications.

Treatment options for MEN typically involve a multidisciplinary approach, including surgery to remove tumors, hormone replacement therapy, and ongoing monitoring to detect any potential tumor recurrence or new developments.