What is the prevalence of Cavernous Malformation?
How many people does Cavernous Malformation affect? Does it have the same prevalence in men and women? And in the different countries?
Cavernous Malformation, also known as Cavernous Angioma or Cerebral Cavernous Malformation, is a relatively rare vascular disorder. It is estimated that the prevalence of Cavernous Malformation ranges from 0.1% to 0.5% in the general population. This means that it affects approximately 1 to 5 individuals per 1,000 people. Although it may seem uncommon, it is important to note that the actual prevalence might be higher due to undiagnosed cases. Cavernous Malformation can occur in various parts of the body, but it is most commonly found in the brain and spinal cord.
Cavernous Malformation, also known as Cavernous Angioma or Cerebral Cavernous Malformation (CCM), is a relatively rare vascular disorder affecting the central nervous system. It is characterized by the presence of abnormal blood vessels, or caverns, in the brain or spinal cord.
The prevalence of Cavernous Malformation varies across different populations and regions. Studies suggest that it affects approximately 0.1% to 0.5% of the general population. However, it is important to note that the true prevalence may be higher due to undiagnosed cases or those without symptoms.
Cavernous Malformation can occur sporadically or be inherited through an autosomal dominant pattern. In familial cases, the prevalence is estimated to be around 0.3% to 0.5% of the population. These cases are often associated with mutations in specific genes, such as CCM1, CCM2, and CCM3.
While Cavernous Malformation can affect individuals of any age, it is often diagnosed in adulthood. The condition may remain asymptomatic or present with various neurological symptoms, including seizures, headaches, focal neurological deficits, or hemorrhages.
Early detection, accurate diagnosis, and appropriate management are crucial in effectively managing Cavernous Malformation and minimizing potential complications.
