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What is the prevalence of Acromegaly?

How many people does Acromegaly affect? Does it have the same prevalence in men and women? And in the different countries?

Prevalence of Acromegaly

Acromegaly is a rare hormonal disorder characterized by excessive growth hormone production in adulthood. It affects approximately 60 out of every million people worldwide, making it a relatively uncommon condition. The prevalence of acromegaly is estimated to be around 3 to 4 cases per 100,000 individuals. Although it is considered rare, early diagnosis and treatment are crucial to prevent potential complications. Acromegaly is typically caused by a benign tumor in the pituitary gland, known as a pituitary adenoma. Symptoms often develop gradually and can include enlarged hands and feet, facial changes, joint pain, and organ enlargement.



Acromegaly is a rare endocrine disorder characterized by excessive growth hormone (GH) production in adulthood. It is estimated that the prevalence of acromegaly is approximately 40 to 125 cases per million people worldwide. Although considered a rare condition, it is important to note that acromegaly often goes undiagnosed or misdiagnosed due to its slow progression and subtle symptoms.



The prevalence of acromegaly varies across different populations, with slightly higher rates reported in certain regions. The condition affects both males and females equally and typically manifests between the ages of 30 and 50. Acromegaly is primarily caused by benign tumors in the pituitary gland called pituitary adenomas, which lead to excessive GH secretion.



Early diagnosis and treatment are crucial to prevent complications associated with acromegaly, such as cardiovascular disease, diabetes, and joint problems. Common symptoms include enlarged hands and feet, facial changes, joint pain, and organ enlargement. If left untreated, acromegaly can significantly impact an individual's quality of life.



It is important for healthcare professionals to be aware of the prevalence of acromegaly and consider it as a potential diagnosis in patients presenting with characteristic symptoms. Timely diagnosis and appropriate management can help improve outcomes and prevent long-term complications.


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