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Is Acute Disseminated Encephalomyelitis hereditary?

Here you can see if Acute Disseminated Encephalomyelitis can be hereditary. Do you have any genetic components? Does any member of your family have Acute Disseminated Encephalomyelitis or may be more predisposed to developing the condition?

Is Acute Disseminated Encephalomyelitis hereditary?

Acute Disseminated Encephalomyelitis (ADEM) is not considered to be a hereditary condition. It is a rare autoimmune disease that typically occurs after an infection or vaccination. ADEM affects the central nervous system, causing inflammation in the brain and spinal cord. While the exact cause is unknown, it is believed to be triggered by an abnormal immune response. ADEM is not passed down through genes and does not have a hereditary pattern.



Is Acute Disseminated Encephalomyelitis Hereditary?


Acute Disseminated Encephalomyelitis (ADEM) is a rare neurological disorder that primarily affects children and young adults. It is characterized by inflammation in the brain and spinal cord, leading to a variety of symptoms such as fever, headache, confusion, seizures, and weakness. A common question that arises is whether ADEM has a hereditary component.



The current understanding of ADEM suggests that it is not a hereditary condition. Research indicates that ADEM is typically triggered by an immune response to an infection or vaccination. It is considered an autoimmune disorder, where the body's immune system mistakenly attacks its own healthy cells in the central nervous system.



While ADEM is not directly inherited, there may be genetic factors that contribute to an individual's susceptibility to developing the condition. Genetic predisposition refers to the presence of certain genes that increase the likelihood of developing a particular disorder. However, the specific genes associated with ADEM susceptibility have not been identified yet.



Environmental factors and viral infections are believed to play a significant role in triggering ADEM. Infections caused by viruses such as Epstein-Barr, measles, mumps, and rubella have been linked to the development of ADEM. These infections can activate the immune system and lead to an inflammatory response in the brain and spinal cord.



It is important to note that ADEM is a sporadic condition, meaning it occurs randomly and is not passed down from parents to their children. The majority of cases are isolated incidents and do not recur within families. However, in rare cases, there have been reports of multiple family members being affected by ADEM, suggesting a potential genetic component. Further research is needed to understand the underlying genetic factors and their role in ADEM.



Diagnosing ADEM typically involves a combination of clinical evaluation, medical history, and diagnostic tests such as magnetic resonance imaging (MRI) scans. These tests help identify the characteristic brain and spinal cord inflammation associated with ADEM and rule out other possible causes of symptoms.



Treatment for ADEM often involves reducing inflammation and managing symptoms. High-dose corticosteroids, such as methylprednisolone, are commonly used to suppress the immune response and reduce inflammation. Other immunosuppressive therapies may be considered in severe cases. Additionally, supportive care and rehabilitation therapies may be necessary to address specific symptoms and aid in recovery.



In conclusion, Acute Disseminated Encephalomyelitis (ADEM) is not considered a hereditary condition. While genetic factors may contribute to an individual's susceptibility, the exact genes involved have not been identified. ADEM is primarily triggered by environmental factors and viral infections, leading to an autoimmune response in the central nervous system. Further research is needed to better understand the underlying genetic and environmental factors associated with ADEM.


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Our son was 3 when he was diagnosed with ADEM. He just turned 4 on Tuesday. It's been 8 months since his attack set in on his brain and spine. He has recovered very well although he still continues with therapies ot, pt, and speech 2 days a week. 
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At 6yo I developed ADEM from vaccines... had chorea symptoms, and seizures, auditory and visual hallucinations, and headaches, and slurred speech and blurred vision, and wound up in a coma for 5 days... my white cells were at 42k and they were attack...
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This is a bit old & long-winded, so if you wanna cut to the chase, scroll down to 'UPDATE 17.5.17'... otherwise, I hope you read on... On 23rd January 2015, I was admitted to hospital suffering loss of control over my legs, chronic fatigue, blurred ...

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