Clinical Information
A hormonal disorder that occurs when the adrenal glands fail to release adequate amounts of glucocorticoids (cortisol), mineralocorticoids (aldosterone, 11-deoxycorticosterone), and androgens (dehydroepiandrosterone) to meet physiologic needs, despite release of acth from the pituitary.
A rare endocrine or hormonal disorder that occurs when the adrenal glands do not produce enough of the hormone cortisol and in some cases, the hormone aldosterone. It may be due to a disorder of the adrenal glands themselves (primary adrenal insufficiency) or to inadequate secretion of acth by the pituitary gland (secondary adrenal insufficiency).
An adrenal disease characterized by the progressive destruction of the adrenal cortex, resulting in insufficient production of aldosterone and hydrocortisone. Clinical symptoms include anorexia; nausea; weight loss; muscle weakness; and hyperpigmentation of the skin due to increase in circulating levels of acth precursor hormone which stimulates melanocytes.
Disease characterized by hypotension, weight loss, anorexia, weakness, and sometimes a bronze-like melanotic hyperpigmentation of the skin; due to tuberculosis or autoimmune induced disease (hypofunction) of the adrenal glands that results in deficiency of aldosterone and cortisol.
Your adrenal glands are just above your kidneys. The outside layer of these glands makes hormones that help your body respond to stress and regulate your blood pressure and water and salt balance. Addison's disease happens if the adrenal glands don't make enough of these hormones. A problem with your immune system usually causes addison's disease. The immune system mistakenly attacks your own tissues, damaging your adrenal glands. Other causes include infections and cancer. Symptoms include
weight loss
muscle weakness
fatigue that gets worse over time
low blood pressure
patchy or dark skin
lab tests can confirm that you have addison's disease. If you don't treat it, it can be fatal. You will need to take hormone pills for the rest of your life. If you have addison's disease, you should carry an emergency id. It should say that you have the disease, list your medicines and say how much you need in an emergency.
Applicable To
Addison's disease
Autoimmune adrenalitis
Approximate Synonyms
Addison disease
Addison's disease, myopathy
Adrenal calcification
Adrenal insufficiency, primary
Myopathy due to Addison disease
Myopathy in Addison's disease
Primary adrenal insufficiency
Type 1 Excludes
Addison only phenotype adrenoleukodystrophy (E71.528)
amyloidosis (E85.-)
tuberculous Addison's disease (A18.7)
Waterhouse-Friderichsen syndrome (A39.1)
ICD-10-CM E27.1 is grouped within Diagnostic Related Group(s) (MS-DRG v34.0):
643 Endocrine disorders with mcc
644 Endocrine disorders with cc
645 Endocrine disorders without cc/mcc