Which are the symptoms of Adult-onset Stills Disease?

Symptoms of Adult-onset Still's Disease

Adult-onset Still's Disease (AOSD) is a rare inflammatory disorder that primarily affects adults. It is characterized by persistent high fevers, joint pain, and a distinctive salmon-colored rash. The exact cause of AOSD is unknown, and it can be challenging to diagnose due to its similarity to other conditions. However, recognizing the symptoms is crucial for early detection and appropriate treatment.

Fever

The hallmark symptom of AOSD is a persistent high fever that typically spikes in the evening and may reach as high as 104°F (40°C). This fever is often accompanied by extreme fatigue, weakness, and a general feeling of malaise. The fever may last for weeks or even months, with intermittent periods of remission.

Joint Pain and Swelling

Joint pain and swelling are common in AOSD and can affect multiple joints simultaneously. The pain is typically severe and may migrate from one joint to another. The most commonly affected joints include the wrists, knees, ankles, and small joints of the hands and feet. The joint pain is often worse in the morning and improves throughout the day.

Rash

A distinctive salmon-colored rash is a classic feature of AOSD. The rash typically appears during fever episodes and may come and go. It is usually non-itchy and can be found on the trunk, limbs, and sometimes the face. The rash may be accompanied by itching or hives in some cases.

Sore Throat

AOSD can cause a sore throat due to inflammation in the throat and tonsils. This symptom is often associated with difficulty swallowing and may be accompanied by swollen lymph nodes in the neck.

Muscle Pain

Muscle pain or myalgia is another common symptom of AOSD. It can affect various muscle groups and is often described as a deep, aching pain. The muscles may feel tender to the touch, and movement can exacerbate the discomfort.

Enlarged Spleen and Liver

In some cases, AOSD can cause enlargement of the spleen and liver. This can lead to abdominal pain, tenderness, and a feeling of fullness or bloating. It is important to monitor these symptoms as they may indicate complications.

Other Symptoms

Additional symptoms that may occur in AOSD include:

• Weight loss


• Swollen lymph nodes


• Headaches


• Chest pain


• Shortness of breath


• Anemia


• Generalized swelling (edema)

When to Seek Medical Attention

If you experience persistent high fevers, joint pain, and any of the aforementioned symptoms, it is important to seek medical attention. AOSD can be a serious condition that requires proper diagnosis and treatment by a healthcare professional.

It is worth noting that the symptoms of AOSD can vary from person to person, and some individuals may experience milder or atypical symptoms. Therefore, it is essential to consult with a healthcare provider for an accurate diagnosis.