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What is the prevalence of Agenesis Of Corpus Callosum?

How many people does Agenesis Of Corpus Callosum affect? Does it have the same prevalence in men and women? And in the different countries?

Prevalence of Agenesis Of Corpus Callosum

Agenesis of Corpus Callosum (ACC) is a rare congenital brain disorder characterized by the partial or complete absence of the corpus callosum, the structure that connects the two hemispheres of the brain. The prevalence of ACC is estimated to be around 1 in 4,000 live births, making it a relatively uncommon condition. ACC can vary in severity and may be associated with other neurological and developmental abnormalities. Early diagnosis and intervention are crucial for managing the potential challenges and providing appropriate support for individuals with ACC.



Agenesis of Corpus Callosum (ACC) is a rare congenital brain disorder characterized by the partial or complete absence of the corpus callosum, the structure that connects the two hemispheres of the brain. ACC occurs in approximately 1 in 4,000 live births, making it a relatively uncommon condition.


The prevalence of ACC varies depending on the population studied and the diagnostic methods used. It is more commonly diagnosed in individuals with neurological or developmental disorders, such as autism spectrum disorder or intellectual disability. In these populations, the prevalence of ACC can be higher, ranging from 7% to 15%.


ACC can occur as an isolated condition or as part of a syndrome or genetic disorder. It is often associated with other brain abnormalities, such as ventriculomegaly or cortical malformations. The exact cause of ACC is not fully understood, but both genetic and environmental factors may play a role.


Early diagnosis and intervention are crucial for individuals with ACC to optimize their development and manage associated symptoms. Treatment typically involves a multidisciplinary approach, including therapies tailored to address specific challenges related to motor skills, communication, and social interaction.


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3 answers
ACC is rare but not as rare as it used to be. There are about 1million of us and that number grows daily and babies and adults are diagnosed

Posted Sep 11, 2017 by Nickie 2500
Adults I dont know any

Posted Oct 30, 2017 by alex 3050

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Mason Cayden Hunter-Colyer Born 11 March 2016 Diagnosis 19 weeks in utero There is also a duplication on his X chromosome that they believe is unrelated and will have no effect. At 18 months old he is a tornado on two legs with no delays, he's ...
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My infant son was diagnosed via fetal MRI in utero with p-acc and slightly enlarged ventricles.
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