Alveolar Capillary Dysplasia synonyms

Alveolar Capillary Dysplasia (ACD) is a rare and life-threatening disorder that affects the development of the lungs in newborns. It is also known by several other names, including Congenital Alveolar Capillary Dysplasia, ACDMPV (Alveolar Capillary Dysplasia with Misalignment of Pulmonary Veins), and Pulmonary Venous Developmental Anomaly.

This condition is characterized by abnormal development of the alveoli, which are tiny air sacs in the lungs responsible for oxygen exchange. In ACD, the alveoli fail to form properly, leading to severe respiratory distress and inadequate oxygenation of the blood. This can result in respiratory failure shortly after birth.

ACD is a genetic disorder, although the exact cause is not yet fully understood. It is believed to be caused by mutations in certain genes that are involved in the development of the pulmonary vasculature. The condition is typically sporadic, meaning it occurs randomly and is not inherited from parents. However, in some cases, it can be inherited in an autosomal recessive pattern.

The symptoms of ACD usually become apparent shortly after birth, with affected infants experiencing rapid breathing, cyanosis (bluish discoloration of the skin), and difficulty feeding. The severity of the symptoms can vary, but the prognosis is generally poor, with most affected infants not surviving beyond the first few months of life.

Diagnosis of ACD is challenging and often requires a combination of clinical evaluation, imaging studies (such as chest X-rays and echocardiography), and genetic testing. Unfortunately, there is currently no cure for ACD, and treatment options are limited. Supportive care, including mechanical ventilation and oxygen therapy, is provided to manage the respiratory distress and improve oxygenation.

In conclusion, Alveolar Capillary Dysplasia is a rare and life-threatening disorder that affects the development of the lungs in newborns. It is also known as Congenital Alveolar Capillary Dysplasia, ACDMPV, or Pulmonary Venous Developmental Anomaly. The condition is characterized by abnormal development of the alveoli, leading to severe respiratory distress and inadequate oxygenation. ACD is a genetic disorder, and while the exact cause is not fully understood, it is believed to be caused by mutations in certain genes involved in pulmonary vasculature development. The prognosis for ACD is generally poor, with most affected infants not surviving beyond the first few months of life. Diagnosis is challenging and treatment options are limited to supportive care.