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What is the prevalence of Aplasia Cutis Congenita (ACC)?

How many people does Aplasia Cutis Congenita (ACC) affect? Does it have the same prevalence in men and women? And in the different countries?

Prevalence of Aplasia Cutis Congenita (ACC)

Aplasia Cutis Congenita (ACC) is a rare condition characterized by the absence of skin at birth. The prevalence of ACC varies widely, ranging from 1 in 10,000 to 1 in 500,000 live births. It is considered a rare disorder, affecting a small percentage of the population. ACC can occur anywhere on the body but is most commonly found on the scalp. The exact cause of ACC is unknown, but it is believed to be a combination of genetic and environmental factors. Early diagnosis and appropriate medical management are crucial for the optimal outcome of affected individuals.



Aplasia Cutis Congenita (ACC) is a rare congenital disorder characterized by the absence of skin at birth. The prevalence of ACC varies depending on the population studied and the specific subtype of the condition. However, it is estimated to occur in approximately 1 in 10,000 to 1 in 20,000 live births.


ACC can present in different forms, ranging from small, localized skin defects to larger areas of missing skin, often accompanied by underlying tissue and bone abnormalities. The condition can affect any part of the body, but it most commonly occurs on the scalp, followed by the trunk and limbs.


The exact cause of ACC is not fully understood, but it is believed to result from a combination of genetic and environmental factors. In some cases, ACC may be associated with other congenital anomalies or genetic syndromes.


Management of ACC depends on the size and location of the skin defect, as well as the presence of any associated abnormalities. Treatment options may include wound care, surgical repair, and addressing any underlying conditions.


While ACC is a rare condition, it is important for healthcare providers to be aware of its existence and potential complications in order to provide appropriate care and support to affected individuals and their families.


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