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What is the history of Behcet Syndrome?

When was Behcet Syndrome discovered? What is the story of this discovery? Was it coincidence or not?

History of Behcet Syndrome

Behcet's Syndrome:


Behcet's syndrome, also known as Behcet's disease, is a rare chronic inflammatory disorder that affects multiple systems in the body. It was first described by a Turkish dermatologist named Hulusi Behcet in 1937. Behcet's syndrome is characterized by recurrent oral and genital ulcers, skin lesions, eye inflammation, and various other symptoms.


Early Observations:


The history of Behcet's syndrome can be traced back to ancient times, although it was not recognized as a distinct medical condition until the 20th century. Historical records suggest that similar symptoms to those seen in Behcet's syndrome were described in ancient Chinese, Greek, and Arab medical texts.


Recognition by Hulusi Behcet:


In 1937, Hulusi Behcet, a Turkish dermatologist, published a detailed report on a group of patients who presented with a unique combination of symptoms. He observed that these patients had recurrent oral and genital ulcers, skin lesions, and eye inflammation. Behcet's findings were significant as he recognized the distinct pattern of symptoms and proposed that it represented a new clinical entity.


Further Research and Classification:


Following Behcet's initial observations, further research was conducted to understand the syndrome better. In the 1960s, the International Study Group for Behcet's Disease was formed to establish diagnostic criteria and classify the disease. This group played a crucial role in standardizing the diagnosis and classification of Behcet's syndrome, enabling better understanding and research.


Geographical Distribution:


Behcet's syndrome is more prevalent in certain regions, particularly along the ancient Silk Road, which connected Asia, the Middle East, and Europe. It is more commonly seen in countries such as Turkey, Iran, Japan, and Korea. However, cases have been reported worldwide, including in Europe and the Americas.


Pathogenesis and Treatment:


The exact cause of Behcet's syndrome remains unknown, but it is believed to involve a combination of genetic, environmental, and immunological factors. The immune system's abnormal response leads to inflammation and damage in various organs. Treatment aims to control symptoms and prevent complications, typically involving medications to suppress the immune system and manage specific symptoms.


Ongoing Research:


Research into Behcet's syndrome continues to advance our understanding of the disease. Scientists are investigating genetic factors, potential triggers, and the underlying mechanisms of inflammation. Ongoing studies aim to develop more targeted and effective treatments for this complex disorder.


Diseasemaps
4 answers
It was discovered & labeled by a Turkish dermatologist in 1936.

Posted Sep 17, 2017 by Carole-Anne Halsey 2000
In 1937, a Turkish dermatologist, Hulusi Behcet, discovered the association of oral and genital ulcerations with hypopyon-uveitis. Americans pronounce is Bah-shetts; however it is French and should be pronounced Bah-Cheys. Since then, Behcet’s Disease was associated with vasculitis. The disease is recognized worldwide, but there are significant differences in the epidemiological, genetic and clinical characteristics of the disorder between ethnic groups and in different geographic locations. As there are no specific manifestations nor specific diagnostic tests, the term "Behcet’s Syndrome" is preferred by some, especially for patients from low-prevalence areas whose disease manifestations are generally less severe and possibly due to other underlying conditions (known as the trisomy of Behcet's which is EDS, POTS, and MCAD). The disease is associated with significant morbidity and mortality if not treated. Treatment is dependent on the site and severity of manifestations. In America, it is considered a faux pas to call BD Behcet's Syndrome because it took many years to have it classified as a disease. The medical community doesn't tend to take syndromes as seriously.

Posted Mar 16, 2022 by Shelby 2750
Translated from spanish Improve translation
It is a enfeedad that develops in the silk route and was dedcrita by a physician turk, who gave his name to the Behcet's disease

Posted Sep 17, 2017 by Salvador 2000

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