What is the prevalence of Biotinidase Deficiency?
How many people does Biotinidase Deficiency affect? Does it have the same prevalence in men and women? And in the different countries?
Biotinidase Deficiency is a rare inherited disorder that affects the body's ability to process biotin, a B-vitamin. It is estimated to occur in approximately 1 in every 60,000 to 120,000 newborns worldwide. This condition can lead to various symptoms such as seizures, developmental delays, skin rashes, and hair loss. Early diagnosis and treatment with biotin supplements can prevent or alleviate these symptoms. It is crucial for healthcare professionals to be aware of this condition and conduct appropriate screening tests to ensure timely intervention for affected individuals.
Biotinidase Deficiency Prevalence:
Biotinidase deficiency is a rare inherited metabolic disorder that affects the body's ability to process biotin, a vitamin essential for various bodily functions. It is estimated that the prevalence of biotinidase deficiency is approximately 1 in every 60,000 to 100,000 newborns worldwide.
This condition is more commonly observed in certain populations, such as individuals of Ashkenazi Jewish descent, where the prevalence can be as high as 1 in every 40,000 newborns. Additionally, it is more frequently diagnosed in countries with expanded newborn screening programs.
Early detection and treatment are crucial for individuals with biotinidase deficiency to prevent potential complications. With prompt intervention, affected individuals can lead normal, healthy lives by receiving lifelong biotin supplementation.
