Is it advisable to do exercise when affected by Birt-Hogg-Dubé syndrome? Which activities would you suggest and how intense should they be?

Birt-Hogg-Dubé syndrome (BHDS) is a rare genetic disorder that affects the skin, lungs, and kidneys. It is caused by mutations in the FLCN gene, which leads to the development of benign skin tumors, lung cysts, and an increased risk of kidney cancer. While exercise is generally beneficial for overall health, it is important for individuals with BHDS to approach exercise with caution and consider certain factors.

Consulting with a healthcare professional is crucial before starting any exercise regimen, especially for individuals with BHDS. They can provide personalized guidance based on the individual's specific condition, overall health, and any existing symptoms or complications.

Low-impact aerobic exercises are generally recommended for individuals with BHDS. These exercises are gentle on the joints and minimize the risk of injury. Some suitable activities include:

• Walking: Walking is a low-impact exercise that can be easily incorporated into daily routines. It helps improve cardiovascular health and overall fitness.


• Cycling: Cycling, whether outdoors or on a stationary bike, is another low-impact exercise that can be beneficial for individuals with BHDS. It helps strengthen the lower body muscles and improves cardiovascular endurance.


• Swimming: Swimming is a great option as it provides a full-body workout without putting excessive stress on the joints. It helps improve cardiovascular fitness, muscle strength, and flexibility.


• Yoga: Yoga combines gentle movements, stretching, and breathing exercises. It can help improve flexibility, balance, and overall well-being.

Intensity of exercise should be determined based on the individual's fitness level, overall health, and any existing symptoms or complications. It is important to start at a comfortable intensity and gradually increase it over time. Monitoring heart rate during exercise can be helpful in ensuring that the intensity is appropriate.

Listening to the body is crucial for individuals with BHDS. It is important to pay attention to any symptoms or discomfort during exercise. If any pain, shortness of breath, dizziness, or other concerning symptoms occur, it is essential to stop exercising and seek medical advice.

Strength training exercises should be approached with caution for individuals with BHDS. Heavy lifting or exercises that put excessive strain on the muscles and joints may increase the risk of injury. If strength training is desired, it is important to work with a qualified fitness professional who can provide guidance on appropriate exercises and techniques.

Overall, exercise can be beneficial for individuals with BHDS as long as it is approached with caution and personalized guidance from healthcare professionals. Low-impact aerobic exercises, such as walking, cycling, swimming, and yoga, are generally recommended. The intensity should be gradually increased based on individual capabilities, and any symptoms or discomfort should be monitored closely. Strength training exercises should be approached with caution and under professional guidance. Remember to always consult with a healthcare professional before starting or modifying any exercise regimen.