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What is the prevalence of C3 Glomerulopathy C3G?

How many people does C3 Glomerulopathy C3G affect? Does it have the same prevalence in men and women? And in the different countries?

Prevalence of C3 Glomerulopathy C3G

C3 Glomerulopathy (C3G) is a rare kidney disorder characterized by abnormal deposits of the protein C3 in the glomeruli, which are the filtering units of the kidneys. The prevalence of C3G is not well-defined due to its rarity and underdiagnosis. However, it is estimated to affect approximately 1-3 individuals per million population. C3G can occur at any age, but it is more commonly diagnosed in adolescents and young adults. Early recognition and proper management are crucial for improving outcomes in individuals with C3G.

C3 Glomerulopathy (C3G) is a rare kidney disorder characterized by abnormal deposits of a protein called C3 in the glomeruli, which are the tiny blood vessels in the kidneys responsible for filtering waste and excess fluid from the blood. C3G is a type of glomerulonephritis, a group of diseases that cause inflammation and damage to the glomeruli.


The prevalence of C3G is not well-established due to its rarity and the challenges in diagnosing the condition. However, studies suggest that it may account for approximately 1-3% of all glomerulonephritis cases. C3G can affect individuals of all ages, including children and adults, with a slight male predominance.


Although C3G is considered a rare disease, it is important to note that prevalence estimates may vary depending on the population studied and the diagnostic criteria used. Further research and awareness are needed to better understand the true prevalence of C3G and improve diagnosis and treatment options for affected individuals.


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Prevalence of C3 Glomerulopathy C3G

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Daughter diagnosed with DDD in 2013, no kidney function and on PD for 4 years awaiting kidney Transplant.

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