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What is the prevalence of Castleman disease?

How many people does Castleman disease affect? Does it have the same prevalence in men and women? And in the different countries?

Prevalence of Castleman disease

Castleman disease is a rare and complex disorder characterized by abnormal growth of lymphatic cells. It is considered a rare disease, with an estimated prevalence of approximately 1 in 100,000 individuals. Although it can affect people of all ages, it is more commonly diagnosed in adults between the ages of 30 and 40. Castleman disease can manifest in localized or multicentric forms, with the latter being more prevalent. Multicentric Castleman disease is even rarer, affecting approximately 5 to 20 individuals per million. Early diagnosis and appropriate management are crucial for individuals affected by this condition.

Castleman disease is a rare and complex disorder that affects the lymph nodes and related tissues. It was first described by Dr. Benjamin Castleman in the 1950s. The prevalence of Castleman disease is relatively low, with an estimated incidence of 1 in 100,000 individuals. However, it is important to note that the prevalence may vary depending on the subtype of the disease.


Castleman disease can occur at any age, but it is most commonly diagnosed in individuals between the ages of 30 and 40. There are two main subtypes of Castleman disease: unicentric and multicentric. Unicentric Castleman disease is localized and typically presents as a single enlarged lymph node, while multicentric Castleman disease involves multiple lymph nodes and can affect various organs.


Although Castleman disease is considered rare, it is crucial to raise awareness about this condition to ensure early diagnosis and appropriate management. Further research and collaboration among healthcare professionals are necessary to better understand the prevalence, causes, and treatment options for Castleman disease.


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Desde 2012, aparece bolita en el cuello, se hace biopsia PAFF da Sindrome Linfoproliferativo, se pide operar para biopsiar mejor, ahi el 31/10/12 se hace, el resultao Enfermedad de Castleman, y comienza el peregrinar, mas de 10 sesiones de Quimiotera...
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I was diagnosed with UCD in 2009 and had a large mesenteric mass removed along with a right hemi colectomy. I have had quite a few complications following, ie incisional hernias, bowel adhesions and bile acid malabsorption . Even though I am told tha...

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