1

Which are the symptoms of Centronuclear Myopathy?

See the worst symptoms of affected by Centronuclear Myopathy here

Centronuclear Myopathy symptoms

Centronuclear Myopathy (CNM) is a rare genetic muscle disorder that primarily affects skeletal muscles, which are responsible for voluntary movements. It is characterized by muscle weakness and abnormal positioning of the nuclei within the muscle cells, hence the name "centronuclear."



Symptoms:



1. Muscle Weakness: One of the hallmark symptoms of CNM is muscle weakness, which can vary in severity. It typically affects the muscles closest to the center of the body, such as the neck, shoulders, hips, and thighs. Weakness may also be present in the facial muscles, causing difficulties with swallowing, speaking, and facial expressions.



2. Delayed Motor Development: Infants with CNM often experience delayed motor development. They may have difficulty achieving milestones such as sitting, crawling, and walking. The weakness in the muscles can make it challenging for them to perform these movements.



3. Respiratory Problems: Some individuals with CNM may develop respiratory complications due to weakness in the muscles involved in breathing. This can lead to difficulties with breathing, especially during sleep or physical exertion. In severe cases, respiratory support may be required.



4. Joint Contractures: Joint contractures, where the joints become fixed in a bent or flexed position, can occur in individuals with CNM. This can affect mobility and range of motion, making it difficult to perform certain movements.



5. Muscle Wasting: Over time, individuals with CNM may experience muscle wasting or atrophy. This can result in a decrease in muscle size and bulk, further contributing to weakness and functional limitations.



6. Ptosis: Ptosis refers to drooping of the upper eyelids. It is a common feature in CNM and can affect one or both eyes. Ptosis can impair vision and may require surgical intervention in some cases.



7. Swallowing Difficulties: Weakness in the muscles involved in swallowing can lead to difficulties in swallowing food and liquids. This can increase the risk of choking and aspiration.



8. Fatigue: Many individuals with CNM experience fatigue, which can be both physical and mental. The constant effort required to compensate for muscle weakness can be draining and impact daily activities.



9. Cardiac Involvement: In rare cases, CNM may be associated with cardiac abnormalities, such as arrhythmias or cardiomyopathy. Regular cardiac evaluations are recommended for individuals with CNM to monitor and manage any potential cardiac issues.



It is important to note that the severity and specific symptoms of CNM can vary widely among affected individuals. Some individuals may have mild symptoms and lead relatively normal lives, while others may experience significant disability and require assistance with daily activities.


Diseasemaps
2 answers
In my experience, adult onset CNM symptoms begin with: muscle wasting, loss of mobility, pain, falling, muscle twitches, no longer able to walk distances or climb stairs, CNM is a progressive, degenerative disease.

Posted Feb 18, 2018 by Kimberly 1850

Centronuclear Myopathy symptoms

Centronuclear Myopathy life expectancy

What is the life expectancy of someone with Centronuclear Myopathy?

3 answers
Celebrities with Centronuclear Myopathy

Celebrities with Centronuclear Myopathy

1 answer
Is Centronuclear Myopathy hereditary?

Is Centronuclear Myopathy hereditary?

3 answers
Is Centronuclear Myopathy contagious?

Is Centronuclear Myopathy contagious?

3 answers
Natural treatment of Centronuclear Myopathy

Is there any natural treatment for Centronuclear Myopathy?

2 answers
ICD9 and ICD10 codes of Centronuclear Myopathy

ICD10 code of Centronuclear Myopathy and ICD9 code

3 answers
Living with Centronuclear Myopathy

Living with Centronuclear Myopathy. How to live with Centronuclear Myopathy...

2 answers
Centronuclear Myopathy diet

Centronuclear Myopathy diet. Is there a diet which improves the quality of ...

2 answers

World map of Centronuclear Myopathy

Find people with Centronuclear Myopathy through the map. Connect with them and share experiences. Join the Centronuclear Myopathy community.

Stories of Centronuclear Myopathy

CENTRONUCLEAR MYOPATHY STORIES

Tell your story and help others

Tell my story

Centronuclear Myopathy forum

CENTRONUCLEAR MYOPATHY FORUM

Ask a question and get answers from other users.

Ask a question

Find your symptoms soulmates

From now on you can add your symptoms in diseasemaps and find your symptoms soulmates. Symptoms soulmates are people with similar symptoms to you.

Symptoms soulmates

Add your symptoms and discover your soulmates map

Soulmates map