Charcot-Marie-Tooth Disease synonyms

Charcot-Marie-Tooth Disease Synonyms

Charcot-Marie-Tooth Disease (CMT) is a hereditary neurological disorder that affects the peripheral nerves, resulting in muscle weakness and sensory loss. It is also known by several other names, including:

• Hereditary Motor and Sensory Neuropathy (HMSN): This term is often used interchangeably with CMT. It highlights the motor and sensory nerve involvement in the disease.


• Peroneal Muscular Atrophy (PMA): PMA specifically refers to the muscle wasting and weakness that primarily affects the peroneal muscles in the lower legs.


• Hereditary Motor Sensory Radiculoneuropathy (HMSR): This term emphasizes the involvement of both motor and sensory nerves, as well as the nerve roots.


• Charcot-Marie-Tooth neuropathy (CMTN): CMTN is another name for CMT, highlighting the neuropathic nature of the disease.


• Hereditary Polyneuropathy with Liability to Pressure Palsies (HNPP): HNPP is a related condition caused by a deletion of a specific gene. It shares some clinical features with CMT but is distinct in its genetic cause.

These synonyms are used by healthcare professionals, researchers, and patients to describe the same underlying condition. The various names reflect different aspects of the disease, such as its hereditary nature, motor and sensory nerve involvement, and specific clinical features.

Charcot-Marie-Tooth Disease is the most commonly used term, while the other synonyms provide additional insights into the specific characteristics of the disorder. Regardless of the name used, the condition is characterized by progressive muscle weakness, sensory loss, and other neurological symptoms.