Diagnosed with MS in 1990, had to stop working in 1992, and became secondary/progressive in mid '90's so never qualified for any of the drugs that came on the market because they were only for relapsing/remitting cases. Continued to decline--6.5 on EDSS (disability scale) until March/2011 when I received venoplasty. Great improvements! Now 4 EDSS. 5 years coming up and all improvements holding!