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What is the prevalence of Chronic Granulomatous Disease?

How many people does Chronic Granulomatous Disease affect? Does it have the same prevalence in men and women? And in the different countries?

Prevalence of Chronic Granulomatous Disease

Chronic Granulomatous Disease (CGD) is a rare genetic disorder characterized by a malfunctioning immune system. It affects approximately 1 in every 200,000 to 250,000 individuals worldwide. CGD is caused by mutations in genes responsible for producing certain proteins essential for immune cell function. These mutations impair the ability of immune cells to effectively kill certain types of bacteria and fungi, leading to recurrent and severe infections. Although CGD is a relatively uncommon condition, its impact on affected individuals can be significant. Early diagnosis and appropriate management are crucial for improving outcomes and quality of life for those living with CGD.

Chronic Granulomatous Disease (CGD) is a rare genetic disorder that affects the immune system's ability to fight off certain types of bacterial and fungal infections. It is estimated that the prevalence of CGD is approximately 1 in 200,000 to 250,000 individuals worldwide. Although CGD can affect people of any age, it is usually diagnosed in early childhood.

CGD is caused by mutations in genes that are responsible for producing proteins involved in the immune system's response to infections. These mutations result in the inability of immune cells to produce reactive oxygen species, which are essential for killing bacteria and fungi. As a result, individuals with CGD are more susceptible to recurrent and severe infections, particularly in the lungs, skin, and other organs.

While CGD is a rare condition, it can have a significant impact on the quality of life and overall health of affected individuals. Early diagnosis and appropriate management, including antimicrobial therapy and stem cell transplantation, can help improve outcomes for individuals with CGD. Ongoing research and advancements in treatment options offer hope for better management and potential cures in the future.
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2 answers
Its a really rare disease, mostly children are diagnosed when they are younger.

Posted Dec 24, 2017 by carrie123 3550

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World map of Chronic Granulomatous Disease

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Stories of Chronic Granulomatous Disease

CHRONIC GRANULOMATOUS DISEASE STORIES
Chronic Granulomatous Disease stories
It all started with a hole in my eardrum. I kept having bad headaches so I decided to fix the hole in my eardrum. I had the hole repaired and had a second surgery to remove a tumor that had developed. The tumor crushed my eardrum and I had to have a ...
Chronic Granulomatous Disease stories
Had a ultrasound and ctscan of my abdominal area and they found masses in my spleen and liver and so my Dr confirmed cgd and I'm slowly having them removed well the ones they can
Chronic Granulomatous Disease stories
In March of 2015, one of my twin daughters(2.5yrs old) was in hospital with bacterial pneumonia for the second time. It wasnt improving every time they took her off IV antibiotics so they started doing tests. One of the tests was for CGD. The doctor ...
Chronic Granulomatous Disease stories
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