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Which are the symptoms of Chronic Granulomatous Disease?

See the worst symptoms of affected by Chronic Granulomatous Disease here

Chronic Granulomatous Disease symptoms

Chronic Granulomatous Disease (CGD) is a rare inherited disorder that affects the immune system. It is characterized by the inability of certain white blood cells, called phagocytes, to effectively kill bacteria and fungi. This leads to the formation of granulomas, which are clusters of immune cells that accumulate and cause inflammation in various organs and tissues.



Symptoms:



1. Recurrent Infections: One of the primary symptoms of CGD is the presence of recurrent and severe bacterial and fungal infections. These infections can affect different parts of the body, including the skin, lungs, lymph nodes, liver, and gastrointestinal tract. Common infections include pneumonia, abscesses, skin infections, and deep-seated fungal infections.



2. Granuloma Formation: CGD leads to the formation of granulomas, which are abnormal accumulations of immune cells. These granulomas can develop in various organs, such as the lungs, liver, spleen, and gastrointestinal tract. The presence of granulomas can cause symptoms such as cough, shortness of breath, abdominal pain, and diarrhea.



3. Growth and Development Issues: Children with CGD may experience growth and developmental delays. This can include delayed puberty, slow growth, and delayed tooth eruption.



4. Swollen Lymph Nodes: Enlarged lymph nodes, particularly in the neck, may be observed in individuals with CGD. These swollen lymph nodes can be tender and may persist for an extended period.



5. Chronic Diarrhea: CGD can cause chronic diarrhea, which may be accompanied by abdominal pain and cramping. This symptom is often associated with granuloma formation in the gastrointestinal tract.



6. Delayed Wound Healing: Individuals with CGD may experience delayed wound healing or the development of persistent skin infections. This is due to the impaired ability of phagocytes to effectively eliminate bacteria.



7. Organ Damage: Over time, the repeated infections and inflammation associated with CGD can lead to organ damage. This can affect the lungs, liver, spleen, and gastrointestinal tract, potentially causing long-term complications.



It is important to note that the severity and specific symptoms of CGD can vary among individuals. Some individuals may have milder forms of the disease with fewer symptoms, while others may experience more severe and frequent infections.



If CGD is suspected, it is crucial to consult with a healthcare professional for a proper diagnosis and appropriate management. Treatment options for CGD may include antimicrobial medications to control infections, immunomodulatory therapies, and in some cases, bone marrow transplantation.


Diseasemaps
6 answers
Granulomas at any places in the body. My case affecting liver, lungs, and sinuses on daily basis.

Posted May 23, 2017 by Lislisa 300
Pneumonia and perianal abscesses

Posted May 23, 2017 by Yahya 300
Stabbing lung pain, chest feelong full from inflamation growing and coughing a lot.
Seen on a lung CT scan

Posted Dec 14, 2017 by Janet Verdoorn 1550
Lung infections, skin infections, the symptoms are different with each person, I'm not sure, my disease is in a milder stage right now, I'm not on a lot of medications right now.

Posted Dec 24, 2017 by carrie123 3550
In people with chronic granulomatous disease, the immune system does not work properly, which leaves the body vulnerable to certain types of bacteria and fungi. The features of the condition usually develop in infancy or early childhood; however, milder forms may be diagnosed in the teen years or even in adulthood. The signs and symptoms vary but may include:
- Frequent bacterial and fungal infections
- Granulomas (areas of inflamed tissue), most commonly in the gastrointestinal tract and/or the genitourinary system
- Abscesses that involve the lungs, liver, spleen, bones, or skin
- Swollen lymph nodes
- Persistent diarrhea

Posted Jul 23, 2018 by Wanderer 400

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Stories of Chronic Granulomatous Disease

CHRONIC GRANULOMATOUS DISEASE STORIES
Chronic Granulomatous Disease stories
It all started with a hole in my eardrum. I kept having bad headaches so I decided to fix the hole in my eardrum. I had the hole repaired and had a second surgery to remove a tumor that had developed. The tumor crushed my eardrum and I had to have a ...
Chronic Granulomatous Disease stories
Had a ultrasound and ctscan of my abdominal area and they found masses in my spleen and liver and so my Dr confirmed cgd and I'm slowly having them removed well the ones they can
Chronic Granulomatous Disease stories
In March of 2015, one of my twin daughters(2.5yrs old) was in hospital with bacterial pneumonia for the second time. It wasnt improving every time they took her off IV antibiotics so they started doing tests. One of the tests was for CGD. The doctor ...
Chronic Granulomatous Disease stories
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