What is Congenital Sucrase Isomaltase Deficiency

Congenital Sucrase Isomaltase Deficiency (CSID) is a rare genetic disorder that affects the digestive system. It is characterized by the body's inability to produce enough of the enzymes sucrase and isomaltase, which are responsible for breaking down sugars and starches in the small intestine. This deficiency leads to difficulties in digesting certain carbohydrates, resulting in symptoms such as chronic diarrhea, abdominal pain, bloating, and excessive gas.

CSID is present from birth and can persist throughout a person's life. It is typically diagnosed in infancy or early childhood when symptoms become apparent after introducing solid foods. The severity of the condition can vary, with some individuals experiencing mild symptoms while others may have more severe digestive issues.

Managing CSID involves making dietary modifications to avoid foods that contain sucrose, maltose, and other complex carbohydrates that are difficult to digest. Enzyme replacement therapy may also be prescribed to help improve digestion. It is important for individuals with CSID to work closely with healthcare professionals and registered dietitians to develop a personalized treatment plan.