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What is the prevalence of Cystic Fibrosis?
How many people does Cystic Fibrosis affect? Does it have the same prevalence in men and women? And in the different countries?
Cystic Fibrosis (CF) is a genetic disorder that affects the respiratory and digestive systems. It is one of the most common life-threatening genetic diseases, primarily affecting individuals of European descent. The prevalence of CF varies among different populations, with an estimated 1 in every 3,500 to 4,000 live births being affected worldwide. However, it is important to note that CF can occur in individuals from any ethnic background. Early diagnosis and advancements in treatment have significantly improved the life expectancy and quality of life for individuals with CF.
Cystic Fibrosis (CF) is a genetic disorder that primarily affects the lungs and digestive system. It is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. CF is inherited in an autosomal recessive manner, meaning that both parents must carry a mutated CFTR gene for their child to develop the condition.
The prevalence of CF varies among different populations and ethnic groups. In the United States, approximately 30,000 individuals are living with CF, making it one of the most common genetic disorders. Globally, CF affects around 70,000 people.
The prevalence of CF can also vary geographically. It is more common in populations of European descent, with the highest rates found in individuals of Northern European ancestry. In these populations, the carrier frequency (the proportion of individuals carrying a single CFTR mutation) is estimated to be around 1 in 25 individuals.
Early diagnosis and advancements in treatment have significantly improved the life expectancy and quality of life for individuals with CF. However, it remains a chronic and progressive condition that requires lifelong management and care.
Diseasemaps
Cystic fibrosis affects at least 30,000 people in the United States; between 900 and 1,000 new cases are diagnosed every year (1). One in 29 people of Caucasian ancestry is an unaffected carrier of the CF gene mutation. In the United States, cystic fibrosis occurs at a rate of 1 in 3,400 births.
Posted Jan 18, 2018 by Marieliz Landa 4060
Translated from spanish
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1 of every 10 000 live births
Posted Sep 14, 2017 by Glauco 2000
