18

What is the prevalence of Dejerine Sottas Disease?

How many people does Dejerine Sottas Disease affect? Does it have the same prevalence in men and women? And in the different countries?

Prevalence of Dejerine Sottas Disease

Dejerine-Sottas disease is a rare genetic disorder that affects the peripheral nerves, causing progressive muscle weakness and sensory loss. It is classified as a subtype of Charcot-Marie-Tooth disease (CMT). The prevalence of Dejerine-Sottas disease is estimated to be around 1 in 25,000 to 1 in 30,000 individuals. Symptoms usually appear in early childhood and worsen over time. Genetic mutations in certain genes, such as PMP22, MPZ, and EGR2, are associated with the development of this condition. Early diagnosis and management can help improve the quality of life for individuals affected by Dejerine-Sottas disease.



Dejerine-Sottas disease is a rare genetic disorder that affects the peripheral nerves, causing progressive muscle weakness and sensory loss. It belongs to a group of disorders known as hereditary motor and sensory neuropathies (HMSN).


The prevalence of Dejerine-Sottas disease is estimated to be around 1 in 25,000 to 1 in 29,000 individuals. Although it is considered a rare condition, the exact prevalence may vary across different populations and regions.


This disorder typically manifests in early childhood or adolescence, with symptoms including muscle weakness, difficulty walking, loss of sensation, and impaired reflexes. The severity of symptoms can vary widely, even among affected individuals within the same family.


Dejerine-Sottas disease is caused by mutations in certain genes that are involved in the production of myelin, the protective covering of nerve fibers. These mutations lead to abnormal myelin formation, resulting in nerve damage and the characteristic symptoms of the disease.


While there is currently no cure for Dejerine-Sottas disease, treatment focuses on managing symptoms and improving quality of life. This may involve physical therapy, assistive devices, pain management, and other supportive measures.


Diseasemaps
1 answer

Prevalence of Dejerine Sottas Disease

Dejerine Sottas Disease life expectancy

What is the life expectancy of someone with Dejerine Sottas Disease?

2 answers
Celebrities with Dejerine Sottas Disease

Celebrities with Dejerine Sottas Disease

1 answer
Is Dejerine Sottas Disease hereditary?

Is Dejerine Sottas Disease hereditary?

2 answers
Is Dejerine Sottas Disease contagious?

Is Dejerine Sottas Disease contagious?

2 answers
Natural treatment of Dejerine Sottas Disease

Is there any natural treatment for Dejerine Sottas Disease?

ICD9 and ICD10 codes of Dejerine Sottas Disease

ICD10 code of Dejerine Sottas Disease and ICD9 code

2 answers
Living with Dejerine Sottas Disease

Living with Dejerine Sottas Disease. How to live with Dejerine Sottas Disea...

1 answer
Dejerine Sottas Disease diet

Dejerine Sottas Disease diet. Is there a diet which improves the quality of...

1 answer

World map of Dejerine Sottas Disease

Find people with Dejerine Sottas Disease through the map. Connect with them and share experiences. Join the Dejerine Sottas Disease community.

Stories of Dejerine Sottas Disease

DEJERINE SOTTAS DISEASE STORIES

Tell your story and help others

Tell my story

Dejerine Sottas Disease forum

DEJERINE SOTTAS DISEASE FORUM

Ask a question and get answers from other users.

Ask a question

Find your symptoms soulmates

From now on you can add your symptoms in diseasemaps and find your symptoms soulmates. Symptoms soulmates are people with similar symptoms to you.

Symptoms soulmates

Add your symptoms and discover your soulmates map

Soulmates map