Delayed Pressure Urticaria (DPU) is a type of physical urticaria, which is characterized by the development of hives or welts on the skin in response to pressure or friction. Unlike other forms of urticaria, DPU has a delayed onset, with symptoms typically appearing 4 to 6 hours after pressure is applied to the skin. These symptoms can persist for several hours or even days, causing significant discomfort and distress to those affected.
Hives: The hallmark symptom of DPU is the development of raised, itchy hives on the skin. These hives may vary in size and shape, and they often appear as red or pink welts. The hives can be localized to the area where pressure was applied or may spread to other parts of the body.
Swelling: Along with hives, individuals with DPU may experience swelling in the affected areas. This swelling, known as angioedema, can occur in deeper layers of the skin and may cause a sensation of tightness or discomfort.
Pain and tenderness: The hives and swelling associated with DPU can be accompanied by pain and tenderness in the affected areas. The skin may feel sensitive to touch, and even mild pressure can exacerbate the symptoms.
Delayed onset: One of the distinguishing features of DPU is the delayed onset of symptoms. Unlike other forms of urticaria that typically manifest within minutes, DPU symptoms may take several hours to appear after pressure is applied to the skin. This delayed reaction can make it challenging to identify the trigger.
Long-lasting symptoms: The symptoms of DPU can persist for an extended period, ranging from hours to days. The duration of symptoms can vary between individuals and may even fluctuate within the same person over time. The prolonged nature of DPU can significantly impact daily activities and quality of life.
Systemic symptoms: In some cases, individuals with DPU may experience systemic symptoms, such as fatigue, headache, malaise, or a general feeling of being unwell. These symptoms are thought to be related to the immune response triggered by DPU.
Triggers: Various triggers can provoke DPU symptoms, including pressure from tight clothing, sitting or leaning on hard surfaces, carrying heavy objects, or even wearing a backpack. Identifying and avoiding these triggers can help manage the condition.
Complications: Although rare, complications can arise from DPU, such as cellulitis (skin infection) or lymphangitis (inflammation of lymphatic vessels). These complications may occur if the skin becomes damaged due to persistent scratching or if the hives and swelling lead to secondary infections.
If you suspect you may have Delayed Pressure Urticaria, it is important to consult with a healthcare professional for an accurate diagnosis and appropriate management strategies. Treatment options for DPU may include antihistamines, corticosteroids, or other medications to alleviate symptoms and reduce inflammation.