Dent Disease is a rare genetic disorder that primarily affects the kidneys. It is estimated to have a prevalence of approximately 1 in 30,000 to 40,000 individuals worldwide. This condition predominantly affects males, with symptoms typically appearing in childhood or adolescence. Dent Disease is characterized by the dysfunction of certain kidney cells, leading to the loss of important proteins and minerals in the urine. Although it is a rare disorder, early diagnosis and proper management can significantly improve the quality of life for individuals with Dent Disease.
Dent Disease is a rare genetic disorder that primarily affects the kidneys. It is characterized by the malfunctioning of certain proteins in the kidney tubules, leading to the loss of important substances such as proteins, calcium, and phosphate in the urine. This condition predominantly affects males, with symptoms typically appearing in childhood or adolescence.
Due to its rarity, the prevalence of Dent Disease is not well-established. However, it is estimated to affect approximately 1 in 30,000 to 1 in 100,000 individuals worldwide. The exact number may vary across different populations and regions. Since Dent Disease often goes undiagnosed or misdiagnosed, the actual prevalence could be higher than reported.
Early recognition and diagnosis of Dent Disease are crucial for appropriate management and treatment. Common symptoms include excessive urination, kidney stones, proteinuria (excessive protein in urine), and electrolyte imbalances. Genetic testing can confirm the diagnosis.
While Dent Disease is a rare condition, it is important to raise awareness among healthcare professionals and the general public to ensure timely identification and proper care for affected individuals.