Dubin-Johnson syndrome is a rare genetic disorder that affects the liver's ability to process and excrete bilirubin, a yellow pigment produced by the breakdown of red blood cells. This condition is also known by several other names, including:
Dubin-Johnson syndrome is characterized by a benign course and usually does not cause significant health problems. The main symptom is a persistent yellow discoloration of the skin and eyes, which may fluctuate in intensity. Other associated symptoms can include mild fatigue, abdominal pain, and dark urine. It is important to note that Dubin-Johnson syndrome is a chronic condition and does not typically progress to liver failure or cirrhosis.
While there is no cure for Dubin-Johnson syndrome, the condition can be managed through regular monitoring and supportive care. Treatment focuses on alleviating symptoms and may involve medications to improve liver function. It is essential for individuals with Dubin-Johnson syndrome to maintain a healthy lifestyle, avoid certain medications that can worsen liver function, and follow up with their healthcare provider regularly.