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What is the prevalence of Factor V Leiden?

How many people does Factor V Leiden affect? Does it have the same prevalence in men and women? And in the different countries?

Prevalence of Factor V Leiden

The prevalence of Factor V Leiden varies among different populations. In individuals of European descent, it is estimated to affect approximately 5% to 8% of the population. However, the prevalence is significantly lower in other ethnic groups, such as Asians and Africans. Factor V Leiden is a genetic mutation that increases the risk of developing abnormal blood clots, particularly in veins. It is important for individuals with a family history of blood clotting disorders to consult with healthcare professionals for appropriate screening and management.



Factor V Leiden is a genetic mutation that affects the clotting factor V in the blood, making individuals more prone to abnormal blood clot formation. It is the most common inherited thrombophilia, or blood clotting disorder, among individuals of European descent.


The prevalence of Factor V Leiden varies among different populations. In individuals of European ancestry, it is estimated to affect around 5% of the population. However, the prevalence can be significantly lower in other ethnic groups, such as African, Asian, and Native American populations.


Factor V Leiden is more commonly found in individuals with a personal or family history of blood clots. It is also more prevalent in individuals who have experienced deep vein thrombosis (DVT), pulmonary embolism, or recurrent miscarriages.


It is important to note that not everyone with the Factor V Leiden mutation will develop blood clots, as other factors such as lifestyle, medical conditions, and additional genetic variations can influence the risk. Genetic testing can help identify individuals with this mutation, allowing for appropriate preventive measures and treatment strategies.


Diseasemaps
3 answers
Factor V affects 5-8% of the Caucasian population, with a more common occurance in those with European decent, with a higher rate in women of child bearing age. 1.2% of the African population are affected by factor V.

Posted Sep 1, 2017 by Stacy 2650
Factor five Leiden is now the most common hereditary coagulation disorder in the United States. It is found in 5% of Caucasians and 1.2% of the Afro-American population. FVL has its lowest frequencies among the Hispanic Americans, African Americans and almost never with indigenous people from Asia, America and Australia. The highest reports are seen in Europeans, some areas report as high as 15% of the population as carriers. FVL is autosomal dominant with inheritance. This means that it affects men and women equally and passes from generation to generation.

Posted Dec 28, 2017 by Barbara 4050

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Stories of Factor V Leiden

FACTOR V LEIDEN STORIES
Factor V Leiden stories
I was diagnosed in 2001 after a series of TIA's and a smart neurologist who suspected there was something more to be investigated since I had a history of DVT's and my mother's family has had numerous blood clots.  Since then I was also diagnosed w...
Factor V Leiden stories
My name is MARTIN R. LEMIEUX, and for over 20 years now I’ve survived five DVTS – BLOOD CLOTS in my left leg, one clot in my right leg, and another clot in my left pelvic area. As if that wasn’t enough, I’ve also had to manage three massive c...
Factor V Leiden stories
In 2010 I was pregnant with my son. Late in my pregnancy I started having horrible swelling in my legs. They were hot, red, and huge. I was placed on maternity leave and put on bed rest. My son was born healthy, but I hemorraged and was given a clot...
Factor V Leiden stories
I WAS DIAGNOSED IN MARCH OF THIS YEAR AFTER HAVING MY 2ND PULMONARY EMBOLISM.  THE DOCTORS COULD NOT FIGURE OUT WHERE MY BLOOD CLOTS WERE COMING FROM SINCE I DID NOT HAVE ANY DVT'S.  I HAVE BOTH GENES, SO I WILL BE ON BLOOD THINNERS THE REST OF MY ...
Factor V Leiden stories
In the spring of 2010, I was working and felt that it was a little difficult to bend my right knee / walk - I felt very little swelling / heat so I thought little of it, especially in light of a prior history of having knee problems in that same leg....

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