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Is Factor VII Deficiency hereditary?

Here you can see if Factor VII Deficiency can be hereditary. Do you have any genetic components? Does any member of your family have Factor VII Deficiency or may be more predisposed to developing the condition?

Is Factor VII Deficiency hereditary?

Yes, Factor VII Deficiency is hereditary. It is an inherited bleeding disorder caused by a mutation in the F7 gene. This gene provides instructions for producing a protein called Factor VII, which is essential for blood clotting. When there is a deficiency of Factor VII, it can lead to prolonged bleeding and difficulty in clotting. The condition is passed down from parents to their children through autosomal recessive inheritance.



Factor VII Deficiency is a rare bleeding disorder that affects the blood's ability to clot properly. It is caused by a deficiency or dysfunction of Factor VII, which is a protein involved in the clotting process.


When it comes to the hereditary nature of Factor VII Deficiency, it is typically inherited in an autosomal recessive manner. This means that both parents must carry a copy of the mutated gene for their child to be affected. If both parents are carriers, there is a 25% chance with each pregnancy that their child will inherit the disorder.


It is important to note that not all individuals with Factor VII Deficiency have a family history of the disorder. In some cases, the condition may occur due to a spontaneous mutation in the Factor VII gene.


Genetic testing can be performed to determine if an individual carries the mutated gene responsible for Factor VII Deficiency. This can be particularly useful for individuals with a family history of the disorder or those planning to have children.


While Factor VII Deficiency is primarily hereditary, it is essential to consult with a healthcare professional or a genetic counselor for a comprehensive evaluation and personalized information regarding the specific genetic factors involved.


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Stories of Factor VII Deficiency

FACTOR VII DEFICIENCY STORIES
Factor VII Deficiency stories
My daughter, Rio (7 years old), was diagnosed with a Factor VII deficiency. It was discovered during pre-op blood work, which showed only her PT level and INR were prolonged. At this time we do not know if it was inherited or acquired. She is asympto...
Factor VII Deficiency stories
HI! MY NAME IS GABBY!  IN 2016, I WAS DIAGNOSED WITH AN EXTREMELY RARE BLOOD DISORDER KNOWN AS FACTOR VII DEFICIENCY. ONLY 1 OF 200 CASES KNOWN WORLDWIDE! THIS IS A LIFELONG ILLNESS THAT CAUSES JOINTS IN MY BODY TO BLEED AND PREVENTS MY BLOOD FROM ...
Factor VII Deficiency stories
Hi everyone, myself Devi Ramasamy from South India & I'm severe factor 7 deficient. I have bleeding right from my birth after severe bleeding in my belly button. With lot & lot of bleeding episodes in gum, nose, joints, muscles, GI, hematuria (bleedi...
Factor VII Deficiency stories
hola soy martina, de argentina paciente con deficiencia congenita de FVII , uso profilaxis dos veces por semana porque presento sangrados espontaneos, nariz, moretones, hemartos pre rotulianos ,menorragia... junto a mi familia buscamos toda la inform...

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