Is Familial Adenomatous Polyposis hereditary?

Familial Adenomatous Polyposis (FAP) is indeed a hereditary condition. It is an autosomal dominant disorder, which means that an affected individual has a 50% chance of passing the condition on to each of their children. FAP is caused by mutations in the APC gene, which is responsible for suppressing the growth of polyps in the colon and rectum.

Individuals with FAP develop numerous polyps in their colon and rectum, typically starting in their teenage years. If left untreated, these polyps have a high likelihood of progressing to colorectal cancer. Therefore, early detection and intervention are crucial in managing this condition.

Genetic testing can be performed to identify individuals who carry the APC gene mutation. If a person is found to have the mutation, regular screenings and surveillance can be initiated to monitor the development of polyps and detect any signs of cancer at an early stage.

Treatment options for FAP include regular colonoscopies to remove polyps and, in some cases, surgical removal of the colon and rectum (colectomy). Additionally, certain medications may be prescribed to reduce the number and size of polyps.

It is important for individuals with a family history of FAP to undergo genetic counseling and testing to determine their risk of inheriting the condition. Early identification of FAP can significantly improve outcomes through proactive management and surveillance.