Familial Mediterranean Fever (FMF) is a relatively rare genetic disorder that primarily affects individuals of Mediterranean descent. While exact prevalence rates vary across different populations, it is estimated to affect approximately 1 in 1,000 to 1 in 10,000 individuals in these regions. FMF is characterized by recurrent episodes of fever and inflammation in various parts of the body, particularly the abdomen, chest, and joints. Early diagnosis and treatment are crucial in managing symptoms and preventing complications. If you suspect FMF, it is important to consult with a healthcare professional for proper evaluation and guidance.
Familial Mediterranean Fever (FMF) is a rare genetic disorder characterized by recurrent episodes of fever and inflammation in various parts of the body. It primarily affects individuals of Mediterranean descent, particularly those of Armenian, Jewish, Turkish, and Arab ancestry.
The prevalence of FMF varies among different populations. In the Mediterranean region, where the disorder is most commonly found, the prevalence ranges from 1 in 200 to 1 in 1,000 individuals. However, it is important to note that FMF can also occur in individuals from non-Mediterranean backgrounds, although at a much lower frequency.
FMF is an autosomal recessive disorder, meaning that both parents must carry a mutated gene for their child to be affected. The mutated gene responsible for FMF is called MEFV, and it affects the regulation of inflammation in the body.
While FMF is considered rare, it is important for individuals with Mediterranean ancestry to be aware of the condition and seek medical attention if they experience symptoms such as recurrent fever, abdominal pain, joint inflammation, or chest pain. Early diagnosis and appropriate management can help prevent complications and improve the quality of life for individuals with FMF.