Familial Mediterranean Fever (FMF) is a hereditary autoinflammatory disorder characterized by recurrent episodes of fever and inflammation in various parts of the body. It is also known by several other names, including:
These synonyms are often used interchangeably to describe the same condition, FMF. It is important to note that FMF is caused by mutations in the MEFV gene, which leads to dysregulation of the innate immune system and subsequent episodes of inflammation.
Individuals with FMF typically experience recurrent attacks of fever, accompanied by symptoms such as abdominal pain, chest pain, joint pain, and skin rashes. These episodes can last anywhere from 12 to 72 hours and may occur sporadically or in a regular pattern.
Early diagnosis and treatment of FMF are crucial to manage symptoms and prevent long-term complications. Colchicine, a medication that reduces inflammation, is the mainstay of treatment for FMF. It helps to control the frequency and severity of attacks, as well as prevent the development of amyloidosis, a serious complication of FMF.
In conclusion, Familial Mediterranean Fever (FMF) is a hereditary autoinflammatory disorder known by various synonyms such as Recurrent Polyserositis, Periodic Fever Syndrome, Hereditary Recurrent Fevers, and Armenian Disease. It is characterized by recurrent episodes of fever and inflammation. Early diagnosis and appropriate treatment are essential for managing FMF and preventing complications.