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What is the prevalence of Febrile infection-related epilepsy syndrome - FIRES?

How many people does Febrile infection-related epilepsy syndrome - FIRES affect? Does it have the same prevalence in men and women? And in the different countries?

Prevalence of Febrile infection-related epilepsy syndrome - FIRES

The prevalence of Febrile infection-related epilepsy syndrome (FIRES) is relatively rare. It affects an estimated 1 in 100,000 individuals, primarily children and young adults. FIRES is characterized by a sudden onset of prolonged seizures following a febrile illness, often resulting in severe neurological impairment. The exact cause of FIRES is unknown, and it is considered a rare and severe form of epilepsy. The prognosis for individuals with FIRES is generally poor, with a high mortality rate and significant long-term neurological deficits in survivors.



Febrile infection-related epilepsy syndrome (FIRES) is a rare and severe form of epilepsy that primarily affects children and young adults. It is characterized by the sudden onset of prolonged seizures, often triggered by a febrile infection. FIRES is a devastating condition with a high morbidity and mortality rate.


The prevalence of FIRES is difficult to determine due to its rarity. However, it is estimated to affect approximately 1 in 100,000 individuals. The syndrome typically occurs in previously healthy individuals, with an average age of onset between 3 and 15 years. Boys are slightly more affected than girls.


FIRES is a medical emergency that requires intensive care and aggressive treatment. The seizures associated with FIRES are often resistant to standard antiepileptic medications, making management challenging. The long-term prognosis for individuals with FIRES is variable, with some experiencing significant cognitive and neurological impairments.


Research and understanding of FIRES are still limited, and further studies are needed to unravel its underlying causes and develop more effective treatments. The rarity of the condition emphasizes the importance of raising awareness and supporting affected individuals and their families.


Diseasemaps
2 answers
it is one in 50 thousand children.

Posted Jun 20, 2022 by Carla 4020

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FEBRILE INFECTION-RELATED EPILEPSY SYNDROME - FIRES STORIES
Febrile infection-related epilepsy syndrome - FIRES stories
Isa was a completely healthy baby girl, with a normal development till she was 10 months old, when she had fever for the first time. It was a high fever, almost 40º Celsius. she went to hospital Emergency unit to control the fever. 2 days after, she...
Febrile infection-related epilepsy syndrome - FIRES stories
Estando perfectamente bien de salud (la niña andaba bien comia de todo rara vez se ponia enferma, hablaba perfectamente) y con 2,5 años de edad sufrio su primera crisis. Tres dias anteriores habia sufrido una leve infeccion de garganta y le dio fie...
Febrile infection-related epilepsy syndrome - FIRES stories
Sam was a happy 5 yo boy. 1st year at school , was a sport loving little cheeky kid in late July had a fever for a few days and went to school for 2 days Thursday Friday. on Saturday Sam had his 1st seizure about 1pm and from there the snowball gai...
Febrile infection-related epilepsy syndrome - FIRES stories
6 years old male, over two month in Status Epileptikus
Febrile infection-related epilepsy syndrome - FIRES stories
My Son got FIRES 2 yrs ago when we were in Melbourne Australia, Due to my husband finished his study. Now we are back to Indonesia and ITS so hard to find SUPPORT for Him even some of HIS ,Meds we need to Import from Melb because some of them not ava...

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