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Is Felty Syndrome hereditary?

Here you can see if Felty Syndrome can be hereditary. Do you have any genetic components? Does any member of your family have Felty Syndrome or may be more predisposed to developing the condition?

Is Felty Syndrome hereditary?

Felty Syndrome is a rare autoimmune disorder characterized by the triad of rheumatoid arthritis, an enlarged spleen, and a low white blood cell count. The exact cause of Felty Syndrome is unknown, but it is believed to have a genetic component. While there is no definitive evidence of hereditary transmission, studies suggest that certain genetic factors may increase the risk of developing the condition. Further research is needed to fully understand the genetic basis of Felty Syndrome.



Felty Syndrome is a rare autoimmune disorder that is characterized by the triad of rheumatoid arthritis, an enlarged spleen (splenomegaly), and a low white blood cell count (neutropenia). It primarily affects adults, usually those who have had rheumatoid arthritis for a long time.



As for the hereditary nature of Felty Syndrome, the exact cause of this condition is still unknown. However, research suggests that there may be a genetic component involved in its development. Studies have shown that certain genetic variations may increase the risk of developing rheumatoid arthritis, which is a prerequisite for Felty Syndrome.



Rheumatoid arthritis, the main underlying condition in Felty Syndrome, does have a genetic predisposition. It is believed that a combination of genetic and environmental factors contribute to the development of rheumatoid arthritis. While specific genes associated with rheumatoid arthritis have been identified, it is important to note that having these genetic variations does not guarantee the development of the disease.



Therefore, it can be inferred that while there may be a genetic predisposition for rheumatoid arthritis, which is a prerequisite for Felty Syndrome, the syndrome itself is not directly hereditary. Other factors, such as environmental triggers and individual immune responses, likely play a significant role in the development of Felty Syndrome.


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I found out  I had feltys  syndromes after a blood test,  they have given an infusion for every week for four weeks and I went  Ann I go every six months,   

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