What are the best treatments for Fox Fordyce Disease?

Treatments for Fox Fordyce Disease

Fox Fordyce Disease, also known as apocrine miliaria, is a rare skin condition that primarily affects women. It is characterized by the appearance of small, itchy bumps on the skin, particularly in areas with apocrine sweat glands such as the underarms, breasts, and pubic area. While there is no known cure for Fox Fordyce Disease, there are several treatment options available to manage the symptoms and provide relief.

1. Topical Treatments

Topical treatments are often the first line of defense against Fox Fordyce Disease. These include:

• Corticosteroid creams: These creams help reduce inflammation and itching, providing temporary relief.


• Retinoid creams: These creams help unclog the sweat gland ducts, reducing the formation of bumps.


• Topical antiperspirants: These can help reduce sweating and alleviate symptoms.

2. Oral Medications

In more severe cases, oral medications may be prescribed by a dermatologist. These medications include:

• Antihistamines: These can help relieve itching and reduce inflammation.


• Oral contraceptives: For women, hormonal contraceptives may help regulate sweat gland activity and reduce symptoms.


• Isotretinoin: This medication is derived from vitamin A and can help control the production of sebum, reducing the occurrence of bumps.

3. Laser Therapy

Laser therapy has shown promising results in treating Fox Fordyce Disease. It involves using laser energy to destroy the sweat glands, preventing them from producing excessive sweat and reducing the formation of bumps. Multiple sessions may be required for optimal results.

4. Surgical Excision

In severe cases where other treatments have failed, surgical excision of the affected sweat glands may be considered. This procedure involves removing the sweat glands to prevent further symptoms. However, it is important to note that this is a more invasive option and should be discussed thoroughly with a dermatologist.

5. Self-Care Measures

While there is no cure for Fox Fordyce Disease, certain self-care measures can help manage symptoms and prevent exacerbation:

• Wearing loose-fitting clothing: This allows better airflow and reduces friction on the affected areas.


• Avoiding shaving: Shaving can irritate the skin and worsen symptoms, so opting for alternative hair removal methods may be beneficial.


• Using gentle cleansers: Harsh soaps and cleansers can further irritate the skin, so opting for mild, fragrance-free products is recommended.


• Applying cool compresses: Cool compresses can help soothe itching and reduce inflammation.

It is important to consult with a dermatologist for an accurate diagnosis and personalized treatment plan for Fox Fordyce Disease. They can assess the severity of the condition and recommend the most suitable treatment options based on individual needs.