Gianotti Crosti Syndrome synonyms

Gianotti Crosti Syndrome, also known as papular acrodermatitis of childhood, is a rare and self-limiting viral exanthem that primarily affects young children. This condition is characterized by a distinctive rash that typically appears on the face, buttocks, and extremities.

The synonyms for Gianotti Crosti Syndrome include:

• Papular Acrodermatitis of Childhood


• Papulovesicular Acrolocated Syndrome


• Papular Acrodermatitis


• Papular Acrodermatitis of Gianotti-Crosti


• Papular Acrodermatitis of Childhood with Hepatitis B Virus Infection

Gianotti Crosti Syndrome is commonly associated with viral infections, particularly hepatitis B virus (HBV) and Epstein-Barr virus (EBV). It is believed to be an immune-mediated response to these viral infections, resulting in the characteristic rash.

The rash of Gianotti Crosti Syndrome typically consists of small, red or flesh-colored papules that may be accompanied by mild itching. These papules often have a symmetrical distribution and can be found in clusters. Over time, the papules may evolve into vesicles or pustules before eventually resolving without scarring.

Other clinical features of Gianotti Crosti Syndrome may include:

• Mild fever


• Lymphadenopathy (enlarged lymph nodes)


• Mild hepatomegaly (enlarged liver)


• Splenomegaly (enlarged spleen)


• Constitutional symptoms such as malaise and fatigue

Diagnosis of Gianotti Crosti Syndrome is primarily based on clinical presentation and history of recent viral infection. Laboratory tests, such as serology for hepatitis B and Epstein-Barr virus, may be performed to confirm the association with these viruses.

Treatment for Gianotti Crosti Syndrome is generally supportive and focused on relieving symptoms. This may include the use of topical corticosteroids to reduce itching and inflammation. Most cases of Gianotti Crosti Syndrome resolve spontaneously within a few weeks to months, with no long-term complications.

In conclusion, Gianotti Crosti Syndrome, also known as papular acrodermatitis of childhood, is a viral exanthem primarily affecting young children. It is characterized by a distinctive rash and is commonly associated with viral infections, particularly hepatitis B and Epstein-Barr virus. The condition is self-limiting, and treatment is mainly supportive.