What is the prevalence of Gilberts syndrome?
How many people does Gilberts syndrome affect? Does it have the same prevalence in men and women? And in the different countries?
Gilbert's syndrome is a common genetic liver disorder characterized by elevated levels of bilirubin in the blood. It affects approximately 3-7% of the population worldwide, making it a relatively prevalent condition. The syndrome is usually benign and often goes undiagnosed as symptoms are mild or absent. Gilbert's syndrome is more commonly observed in males than females. While it does not typically require treatment, individuals with this condition may experience occasional jaundice or fatigue. It is important to consult a healthcare professional for proper diagnosis and management.
Gilbert's syndrome is a relatively common genetic disorder that affects the liver's ability to process bilirubin, a yellow pigment produced during the breakdown of red blood cells. It is estimated to affect approximately 3-12% of the general population worldwide, making it one of the most prevalent hereditary liver conditions.
This syndrome is caused by a mutation in the UGT1A1 gene, which leads to reduced activity of the enzyme responsible for bilirubin metabolism. As a result, individuals with Gilbert's syndrome may experience mild jaundice, characterized by a yellowish tint in the skin and eyes, especially during times of stress, fasting, or illness.
While Gilbert's syndrome is generally considered harmless and does not require treatment, it is important for individuals with this condition to be aware of certain factors that can exacerbate symptoms. These include certain medications, such as acetaminophen and some antibiotics, as well as fasting and dehydration.
Although Gilbert's syndrome is a lifelong condition, it does not typically lead to any long-term complications or affect life expectancy. However, it is advisable for individuals with this syndrome to inform their healthcare providers about their condition to ensure appropriate management and avoid unnecessary concerns.
Posted Aug 17, 2017 by Greyhead@lbg 2500
