Gilberts syndrome synonyms

Gilbert's syndrome, also known as Gilbert-Meulengracht syndrome, is a common, benign liver condition that affects the metabolism of bilirubin, a yellow pigment produced during the breakdown of red blood cells. This condition is characterized by intermittent episodes of mild jaundice, which is the yellowing of the skin and eyes.

Synonyms for Gilbert's syndrome:

• Benign unconjugated hyperbilirubinemia


• Constitutional hepatic dysfunction


• Familial nonhemolytic jaundice


• Unconjugated benign bilirubinemia


• Meulengracht syndrome

It is important to note that Gilbert's syndrome is a benign condition, meaning it does not cause any long-term health problems or liver damage. The symptoms of Gilbert's syndrome are usually mild and may include fatigue, abdominal discomfort, and occasional yellowing of the skin and eyes. These symptoms tend to worsen during times of stress, illness, fasting, or dehydration.

Gilbert's syndrome is caused by a genetic mutation that affects the UGT1A1 gene responsible for the production of an enzyme called UDP-glucuronosyltransferase. This enzyme helps in the processing and elimination of bilirubin from the body. In Gilbert's syndrome, there is a reduced activity of this enzyme, leading to a buildup of unconjugated bilirubin in the blood.

Diagnosis of Gilbert's syndrome is typically made through blood tests that measure the levels of bilirubin. The total bilirubin levels are usually mildly elevated, with a higher proportion of unconjugated bilirubin. Other liver function tests are usually normal.

Treatment for Gilbert's syndrome is generally not required as the condition does not cause any significant health problems. However, it is important for individuals with Gilbert's syndrome to avoid triggers that may worsen symptoms, such as fasting, dehydration, and certain medications that can affect bilirubin metabolism. Maintaining a healthy lifestyle, including regular exercise and a balanced diet, can also help manage symptoms.

In conclusion, Gilbert's syndrome, also known as Gilbert-Meulengracht syndrome, is a benign liver condition characterized by intermittent episodes of mild jaundice. It is caused by a genetic mutation affecting the UGT1A1 gene. While the condition does not require treatment, individuals with Gilbert's syndrome should be mindful of triggers that can worsen symptoms. Overall, Gilbert's syndrome is a relatively harmless condition that does not pose any long-term health risks.