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Which are the symptoms of Glanzmanns thrombasthenia?

See the worst symptoms of affected by Glanzmanns thrombasthenia here

Glanzmanns thrombasthenia symptoms

Symptoms of Glanzmann's Thrombasthenia


Glanzmann's thrombasthenia is a rare inherited bleeding disorder characterized by the inability of platelets to properly clot and form blood clots. This condition is caused by a deficiency or dysfunction of a protein called glycoprotein IIb/IIIa, which is essential for platelet aggregation. As a result, individuals with Glanzmann's thrombasthenia may experience various symptoms related to abnormal bleeding.



1. Easy Bruising


One of the most common symptoms of Glanzmann's thrombasthenia is easy bruising. Even minor trauma or pressure on the skin can cause extensive bruising. Bruises may appear larger and take longer to heal compared to individuals without the condition.



2. Prolonged Bleeding


Individuals with Glanzmann's thrombasthenia may experience prolonged bleeding after injuries or surgeries. The blood fails to clot properly, leading to persistent bleeding that is difficult to control. This can be particularly concerning during dental procedures or surgeries.



3. Frequent Nosebleeds


Nosebleeds, medically known as epistaxis, are a common symptom of Glanzmann's thrombasthenia. These nosebleeds can be spontaneous or occur after minor trauma to the nose. They may be difficult to stop and can be recurrent.



4. Heavy Menstrual Bleeding


Women with Glanzmann's thrombasthenia often experience heavy and prolonged menstrual bleeding, known as menorrhagia. This can lead to anemia and may require medical intervention to manage the bleeding and prevent complications.



5. Gastrointestinal Bleeding


In some cases, individuals with Glanzmann's thrombasthenia may experience gastrointestinal bleeding. This can manifest as blood in the stool, black or tarry stools, or vomiting blood. Gastrointestinal bleeding can be serious and may require immediate medical attention.



6. Bleeding from the Gums


Spontaneous bleeding from the gums, even without any trauma or injury, is another symptom of Glanzmann's thrombasthenia. This can occur during brushing, flossing, or even while eating. The bleeding may be difficult to control and may require specialized dental care.



7. Excessive Bleeding after Childbirth


Women with Glanzmann's thrombasthenia are at an increased risk of excessive bleeding after childbirth, known as postpartum hemorrhage. This can be a life-threatening complication and requires immediate medical intervention to manage the bleeding and prevent complications.



8. Easy Bleeding from Minor Cuts or Scratches


Even minor cuts or scratches can result in prolonged bleeding in individuals with Glanzmann's thrombasthenia. The blood fails to clot properly, leading to continuous bleeding from these small wounds. This can be a significant concern for everyday activities.



9. Abnormal Bleeding after Dental Procedures


People with Glanzmann's thrombasthenia may experience abnormal bleeding after dental procedures, such as tooth extractions or gum surgeries. The bleeding may be difficult to control and may require specialized dental care and close monitoring.



10. Excessive Bleeding after Trauma or Surgery


Individuals with Glanzmann's thrombasthenia are at an increased risk of excessive bleeding after trauma or surgical procedures. The blood fails to clot properly, leading to prolonged bleeding that may require medical intervention to control and manage.



If you or someone you know experiences any of these symptoms, it is important to consult with a healthcare professional for a proper diagnosis and appropriate management. Glanzmann's thrombasthenia is a lifelong condition, but with proper medical care and management, individuals can lead fulfilling lives.


Diseasemaps
2 answers
Joint pain , bruising

Posted Mar 7, 2017 by Debbie 1000

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