What is the prevalence of Glucose-Galactose Malabsorption?
How many people does Glucose-Galactose Malabsorption affect? Does it have the same prevalence in men and women? And in the different countries?
Glucose-Galactose Malabsorption is a rare genetic disorder that affects the ability of the small intestine to absorb glucose and galactose, leading to digestive issues. It is estimated that the prevalence of this condition is very low, affecting approximately 1 in every 60,000 to 100,000 individuals worldwide. Due to its rarity, Glucose-Galactose Malabsorption is considered a rare disease. Early diagnosis and proper management are crucial for individuals with this condition to maintain a healthy lifestyle.
Glucose-Galactose Malabsorption (GGM) is a rare genetic disorder that affects the ability of the small intestine to absorb glucose and galactose, two important sugars found in many foods. This condition is caused by mutations in the SGLT1 gene, which is responsible for producing a protein that transports glucose and galactose into the bloodstream.
The prevalence of GGM is extremely low, with only a few hundred cases reported worldwide. It is estimated to affect approximately 1 in every 50,000 to 100,000 individuals. This disorder is typically diagnosed in infancy or early childhood when affected infants are introduced to foods containing glucose and galactose, such as breast milk or formula.
Individuals with GGM experience severe diarrhea, dehydration, and failure to thrive due to the inability to absorb these sugars. Treatment involves strict avoidance of glucose and galactose in the diet, which can be challenging as these sugars are present in many common foods. Instead, alternative sources of energy, such as fructose or complex carbohydrates, are used.
Although GGM is a rare condition, early diagnosis and appropriate dietary management can significantly improve the quality of life for affected individuals.
