What is the prevalence of Granulomatosis with Polyangiitis (GPA)?

Granulomatosis with Polyangiitis (GPA), formerly known as Wegener's granulomatosis, is a rare autoimmune disease characterized by inflammation of blood vessels, primarily affecting the respiratory tract and kidneys. The exact cause of GPA is unknown, but it is believed to involve a combination of genetic and environmental factors.

GPA is considered a rare disease, with an estimated prevalence of 3 to 15 cases per 100,000 individuals worldwide. Although it can affect people of all ages, it most commonly occurs in middle-aged adults. The disease is slightly more prevalent in men than in women.

The symptoms of GPA can vary widely depending on the organs involved, but commonly include sinusitis, lung problems (such as cough, shortness of breath), kidney damage, joint pain, skin rashes, and eye inflammation. If left untreated, GPA can lead to serious complications and organ damage.

Early diagnosis and treatment are crucial to managing GPA and preventing long-term complications. Treatment typically involves a combination of immunosuppressive medications to reduce inflammation and control the autoimmune response. Regular monitoring and follow-up with healthcare professionals are essential for managing the disease effectively.

Disclaimer: This information is provided for educational purposes and should not replace professional medical advice. If you suspect you have GPA or any other medical condition, please consult a healthcare professional for an accurate diagnosis and appropriate treatment.