Can people with Granulomatosis with Polyangiitis (GPA) work? What kind of work can they perform?

Granulomatosis with Polyangiitis (GPA), formerly known as Wegener's granulomatosis, is a rare autoimmune disease that primarily affects the blood vessels in various organs, including the lungs, kidneys, and upper respiratory tract. It is characterized by inflammation and the formation of granulomas, which are small clusters of immune cells.

When it comes to work, the ability of individuals with GPA to continue working largely depends on the severity of their symptoms and the impact of the disease on their overall health and well-being. GPA can vary greatly in its presentation and progression, with some individuals experiencing mild symptoms and others facing more severe complications.

For individuals with mild to moderate GPA symptoms, it may be possible to continue working in their current occupation or make reasonable accommodations to ensure their productivity and well-being. This could involve adjustments such as reduced working hours, flexible schedules, or modifications to the work environment to minimize exposure to triggers that may worsen symptoms.

However, for individuals with more severe GPA symptoms, it may be challenging to maintain regular employment. The disease can cause fatigue, joint pain, respiratory problems, and other debilitating symptoms that may significantly impact a person's ability to perform their job duties. In such cases, individuals may need to consider alternative work options or take a temporary leave of absence until their condition improves.

It is important for individuals with GPA to prioritize their health and well-being. Seeking appropriate medical treatment and adhering to prescribed medications and therapies can help manage symptoms and potentially improve overall functioning. Regular communication with healthcare professionals is crucial in determining the feasibility of continuing work and exploring suitable accommodations.

Some potential work options for individuals with GPA who are unable to continue in their previous occupation or require significant modifications include:

• Transitioning to part-time or flexible work schedules


• Exploring remote work or telecommuting opportunities


• Seeking employment in roles that involve less physical exertion or exposure to triggers, such as administrative or desk-based jobs


• Considering self-employment or freelance work, which allows for greater flexibility and control over working conditions


• Exploring vocational rehabilitation programs that can provide training and support for individuals with disabilities

Ultimately, the ability to work with GPA varies from person to person. It is essential for individuals to consult with their healthcare team, including rheumatologists and occupational therapists, to assess their specific situation and determine the most suitable work options based on their abilities and limitations.