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Which are the causes of Hallucinogen Persistent Perception Disorder?

See some of the causes of Hallucinogen Persistent Perception Disorder according to people who have experience in Hallucinogen Persistent Perception Disorder

Hallucinogen Persistent Perception Disorder causes

Hallucinogen Persistent Perception Disorder (HPPD) is a rare condition characterized by the persistent presence of sensory disturbances, such as visual hallucinations, after the use of hallucinogenic substances. While the exact causes of HPPD are not fully understood, several factors have been identified as potential contributors to the development of this disorder.



Prolonged exposure to hallucinogens: The primary cause of HPPD is the use of hallucinogenic substances, such as LSD, psilocybin mushrooms, or MDMA. These substances can alter the brain's perception and sensory processing, leading to persistent perceptual disturbances even after the effects of the drug have worn off. The frequency and dosage of hallucinogen use may play a role in the development of HPPD, with individuals who have used these substances more frequently or in higher doses being at a higher risk.



Individual susceptibility: Not everyone who uses hallucinogens will develop HPPD, suggesting that individual susceptibility plays a role in the development of this disorder. Some individuals may have a genetic predisposition or underlying vulnerability that makes them more susceptible to the long-term effects of hallucinogens. Factors such as age, mental health history, and overall brain chemistry may influence an individual's susceptibility to HPPD.



Pre-existing mental health conditions: Individuals with pre-existing mental health conditions, such as anxiety disorders or schizophrenia, may be more prone to developing HPPD. Hallucinogens can interact with these underlying conditions and exacerbate symptoms, leading to persistent perceptual disturbances. It is important to note that HPPD can also occur in individuals without a history of mental health issues.



Drug interactions: HPPD can sometimes be triggered or worsened by the use of other substances, including prescription medications or recreational drugs. The combination of hallucinogens with other substances can have unpredictable effects on the brain and may increase the risk of developing HPPD.



Neurological and physiological factors: Some research suggests that HPPD may be associated with abnormalities in brain structure or function. It is possible that certain individuals have unique neurological or physiological characteristics that make them more susceptible to the long-term effects of hallucinogens.



Environmental factors: While less well-studied, environmental factors such as stress, trauma, or exposure to certain toxins may also contribute to the development of HPPD. These factors may interact with hallucinogen use and increase the risk of persistent perceptual disturbances.



In conclusion, the causes of Hallucinogen Persistent Perception Disorder are multifactorial and likely involve a combination of prolonged exposure to hallucinogens, individual susceptibility, pre-existing mental health conditions, drug interactions, neurological and physiological factors, as well as environmental influences. Further research is needed to fully understand the underlying mechanisms and risk factors associated with HPPD.


Diseasemaps
3 answers
They are unknown. Many hypothesies :
- Too much Dopamine
- DNA alteration
- 5HT receptor upregulation or downregulation
- Excess glutamate
- Neuronal damage resulting from excess glutamate
- General brain disinhibition.

These are just to name a few.

Posted Jun 11, 2018 by dayum_som 4020
Every drug that activates the 5-HT 2a or 2c receptors.

E.g. Derivatives of, and including themselves; MDMA, LSD, DMT, psilocin, ketamine, dextromethorphan, etc.


Anything that can cause hallucinations with the exception of carbon based inhalants (nitrous can cause HPPD) can cause HPPD.

Posted Feb 17, 2019 by Nicolas 4550

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Stories of Hallucinogen Persistent Perception Disorder

HALLUCINOGEN PERSISTENT PERCEPTION DISORDER STORIES
Hallucinogen Persistent Perception Disorder stories
I got hppd from taking too much of a drug  ( research chemical) have had visual disturbances since. For example :tracers, visual snow etc 
Hallucinogen Persistent Perception Disorder stories
Youre not going to lose your vision. Ive had it for about 20 years now and from what I can tell and remember its stayed about the same throughout my life. I can still see fine, except for the snow. As for advice id say you need to look at this as any...
Hallucinogen Persistent Perception Disorder stories
I'll make it short and to the point. I had been tripping acid basically on a bi-weekly basis for about 3 to 4 months, and I would take microdoses (very small amounts) to work often just for the extra energy it provides at those doses. It got to a po...
Hallucinogen Persistent Perception Disorder stories
I’ll keep this short.. I made a decision to try MDMA one time in the summer of 2018 at a music festival. I took .15 grams and I weighed about 110 pounds. I am a small female, 21 years old at the time. I did not develop symptoms right away. I notice...
Hallucinogen Persistent Perception Disorder stories
Tried one hit of lsd, didn't experience much.  Tried 6 hits a month later, didn't experience much, but after the effects wore off, some didn't. Month later effects/symptoms remain the same concluding HPPD. Trying my best to find pills and suppleme...

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