Which are the causes of HFE hereditary haemochromatosis?

See some of the causes of HFE hereditary haemochromatosis according to people who have experience in HFE hereditary haemochromatosis

HFE hereditary haemochromatosis causes
8 answers
HFE Hereditary haemochromatosis is genetic. You are born with the risk. It is a recessive genetic condition ie you must inherit one copy of a mutated gene from each parent. Iron overload can occur where there has been mutation of both copies of the HFE gene. Generally only C282Y homozygous (both copies of the gene) leads to serious overload. Sometimes the C282Y / H63D combination will lead to a milder form. Peoplewho have only one gene mutated are carriers but do not express symptoms.

Posted May 21, 2017 by Tony Moorhead 2051
Your parents ... I believe.

Posted Jun 3, 2017 by bewiki 4317
You inherit it from your parents who have 1 or 2 genes

Posted Jul 22, 2017 by Tina 1501
HFE is a genetic condition, so if your mother or father are both carriers of the mutation (or one is a carrier and the other has the condition), you should be tested to make sure you do not have HFE.

Posted Jul 22, 2017 by alohaitsaj 1501
Genetics. Some believe there is a connection to the Vikings.

Posted Jul 22, 2017 by Salena 2001
Genectics are the cause.

Posted Jul 23, 2017 by Warbychick 1901
At least 110 different mutations on at least 6 genes have been identified which may cause too much uptake of iron. The mutations first occurred more than 5,000 years ago. It might be an adaptation from nature to protect against the cold in the north or as some kind of warrior mechanism so people could tolerate to bleed more often. The researchers have over many years speculated over several theories.

The mutations mostly are inherited as autosomal recessive, meaning that you inherit the mutation ion the gene from both parents. Some rare cases of HH could be inherited as a dominant pass on, meaning that it is enough to get the mutation from one of the parents.

Posted Jul 25, 2017 by Ketil Toska 2051
C282Y gene or H63D gene

Posted Aug 2, 2017 by Natalie 2000

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Stories of HFE hereditary haemochromatosis

HFE hereditary haemochromatosis stories
Discover as one of the first in Bergen, Norway. Both my brothers were caught because of me. Become the first blodd donor with Haemochromatosis on Haukeland sykehus. Have 1round 130 accepted blood donations and the double for sience.. Very happy to b...
HFE hereditary haemochromatosis stories
I originally come from Kiel, Germany and moved to the UK in 1985. In 2005, I was finally diagnosed with Hamochromatosis which has affected my joints very badly. After having been venesected for about 6 months in 2005/2006, the arthritis got worse I ...
HFE hereditary haemochromatosis stories
Until March 2016 I did not know I had haemochromotosis, but the signs and symptoms have been there for three years chronic fatigue, aching joints, lack of libido and at times crankier than normal being a working mum of two teenage girls and a wife of...
HFE hereditary haemochromatosis stories
I was feeling sick and went to my GP, who said I need some ferritin tablets and calsuim, well I got it and drank it , like my Gp told me, the following day I started icthing, then it sarted out with big red marks on my arms and all over my body, phon...
HFE hereditary haemochromatosis stories
I was diagnosed three years ago after both my parents tested positive for the HHC genes. My Dad is a C282Y carrier but my mum is Homozygous with 2 copies of the H63D gene, which was sadly diagnosed far too late. Both my sister and myself are Compound...

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