Is Hereditary Hemorrhagic Telangiectasia contagious?

Is Hereditary Hemorrhagic Telangiectasia (HHT) contagious?

No, Hereditary Hemorrhagic Telangiectasia (HHT) is not contagious. HHT, also known as Osler-Weber-Rendu syndrome, is a genetic disorder that is inherited in an autosomal dominant manner. This means that an affected individual has a 50% chance of passing the condition on to each of their children.

HHT is characterized by the development of abnormal blood vessels called telangiectasias throughout the body, particularly in the nose, skin, and internal organs. These fragile blood vessels are prone to bleeding, leading to symptoms such as recurrent nosebleeds, gastrointestinal bleeding, and arteriovenous malformations.

The condition is caused by mutations in certain genes that are involved in the development and maintenance of blood vessels. The most common genes associated with HHT are ENG (endoglin) and ACVRL1 (activin receptor-like kinase 1). These genetic mutations disrupt the normal formation and structure of blood vessels, leading to the characteristic symptoms of HHT.

Since HHT is a genetic disorder, it is important for individuals with a family history of the condition to undergo genetic testing and counseling. This can help identify the specific gene mutation responsible for HHT and provide information about the risk of passing it on to future generations.

It is crucial to note that HHT is not contagious and cannot be transmitted from person to person through any means of contact or exposure. The condition is solely inherited through genetic factors and does not involve any infectious agents or pathogens.