What is the prevalence of Hereditary Spherocytosis?

How many people does Hereditary Spherocytosis affect? Does it have the same prevalence in men and women? And in the different countries?

Hereditary Spherocytosis is a relatively rare inherited blood disorder characterized by abnormal red blood cells that are spherical in shape instead of the usual biconcave shape. It is most commonly found in individuals of Northern European descent, with an estimated prevalence of 1 in 2,000 to 5,000 individuals. The condition is caused by mutations in genes responsible for red blood cell membrane proteins. Symptoms can vary from mild to severe, including anemia, jaundice, and an enlarged spleen. Diagnosis is typically confirmed through blood tests and genetic analysis.

Hereditary Spherocytosis is a relatively rare genetic disorder characterized by abnormal red blood cells that are spherical in shape instead of the normal biconcave shape. These abnormal cells are more prone to being destroyed by the spleen, leading to a condition called hemolytic anemia.

The prevalence of Hereditary Spherocytosis varies among different populations. In general, it is estimated to affect approximately 1 in 2,000 to 5,000 individuals worldwide. However, the prevalence can be higher in certain regions or ethnic groups. For example, in Northern Europe, the prevalence is reported to be around 1 in 2,000 individuals, while in Japan it is estimated to be 1 in 5,000.

Hereditary Spherocytosis is an inherited condition, usually passed down in an autosomal dominant manner, meaning that an affected individual has a 50% chance of passing the condition on to their children. However, the severity of the disorder can vary widely among individuals, with some experiencing mild symptoms while others may require medical intervention.

Early diagnosis and appropriate management are crucial in minimizing complications associated with Hereditary Spherocytosis. If you suspect you or a family member may have this condition, it is important to consult with a healthcare professional for proper evaluation and guidance.

Diseasemaps

I have spherocytosis, hereditary. It is transmitted from parents to children. What if you have the same prevalence in men as in women, depends on which parent of yours has the gene. Mothers who have spend all their male children, with a 50 percent chance of obtaining that gene, in contrast to women will not pass the gene, and men will pass it on to their daughters, with a hundred percent chance that they will get that gene, in contrast to their male children do not.

Posted Jul 20, 2017 by Ainhoa 1100