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What is the prevalence of Histaminosis / Histamine Intolerance?

How many people does Histaminosis / Histamine Intolerance affect? Does it have the same prevalence in men and women? And in the different countries?

Prevalence of Histaminosis / Histamine Intolerance

Histaminosis, also known as Histamine Intolerance, is a condition characterized by an impaired ability to break down histamine, resulting in an excessive accumulation of histamine in the body. While the exact prevalence is unknown, it is estimated to affect approximately 1-3% of the population. Symptoms can vary widely and may include headaches, digestive issues, skin problems, and respiratory symptoms. Diagnosis can be challenging as it requires a thorough evaluation of symptoms and dietary triggers. Treatment typically involves avoiding histamine-rich foods and taking antihistamines to manage symptoms.



Histaminosis, also known as Histamine Intolerance, is a condition characterized by the body's inability to properly break down and metabolize histamine, a chemical compound involved in various bodily functions. When histamine levels exceed the body's capacity to process it, symptoms such as headaches, digestive issues, skin problems, and respiratory difficulties may arise.


While the exact prevalence of histaminosis is not well-established, it is believed to be more common than previously recognized. The condition often goes undiagnosed or misdiagnosed due to its similarity to other disorders. However, recent studies suggest that histamine intolerance may affect up to 1% of the population, with higher prevalence in certain groups such as middle-aged women.


It is important to note that histaminosis is a complex and multifactorial condition, and its diagnosis can be challenging. The symptoms can vary widely among individuals, making it difficult to pinpoint the cause. A thorough medical evaluation, including a detailed history and elimination diet, is typically necessary to diagnose histamine intolerance.


If you suspect you may have histaminosis, it is recommended to consult with a healthcare professional who can provide appropriate guidance and support.


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