Holmes-Adie Syndrome is a rare neurological disorder characterized by a dilated pupil and reduced or absent reflexes. The condition is generally benign and does not significantly affect life expectancy. Individuals with Holmes-Adie Syndrome can lead normal, healthy lives with proper management and care. However, it is important to note that the prognosis may vary depending on associated conditions or complications. Regular medical check-ups and appropriate treatment can help manage symptoms and improve quality of life for those affected by this syndrome.