Hypokalemic periodic paralysis, also known as familial hypokalemic periodic paralysis (FHPP), is a rare genetic disorder characterized by episodes of muscle weakness or paralysis. It is typically caused by a mutation in the gene responsible for controlling the movement of potassium ions in muscle cells.
During an episode of hypokalemic periodic paralysis, individuals experience sudden attacks of muscle weakness or paralysis, often triggered by factors such as high carbohydrate meals, strenuous exercise, stress, or certain medications. These episodes can last from a few hours to several days and may affect various muscle groups, including the arms, legs, and trunk.
The term "hypokalemic" refers to the low levels of potassium in the blood that occur during an episode. Potassium plays a crucial role in muscle function, and a deficiency can disrupt the normal electrical signals that control muscle contractions.
There are several synonyms used to describe hypokalemic periodic paralysis, including:
It is important to note that hypokalemic periodic paralysis is a chronic condition that requires ongoing management. Treatment options may include lifestyle modifications, such as avoiding triggers and maintaining a balanced diet, as well as medications to regulate potassium levels and prevent or shorten episodes.
If you or someone you know experiences symptoms of hypokalemic periodic paralysis, it is essential to consult with a healthcare professional for an accurate diagnosis and appropriate management strategies.