Hypoparathyroidism, also known as parathyroid hormone deficiency, is a rare endocrine disorder characterized by insufficient production or secretion of parathyroid hormone (PTH) by the parathyroid glands. These small glands are located in the neck, near the thyroid gland, and play a crucial role in regulating calcium and phosphorus levels in the body.
When the parathyroid glands fail to produce adequate amounts of PTH, it leads to a disruption in the body's calcium balance. This condition can be either congenital (present at birth) or acquired (developed later in life). Congenital hypoparathyroidism is often caused by genetic mutations, while acquired hypoparathyroidism can result from surgical removal of the parathyroid glands, autoimmune disorders, or damage to the glands due to radiation therapy.
Symptoms of hypoparathyroidism can vary in severity and may include:
Treatment for hypoparathyroidism typically involves lifelong supplementation of calcium and vitamin D to maintain normal calcium levels in the blood. This may include oral calcium and active vitamin D analogs. Regular monitoring of calcium levels is essential to adjust the dosage of medications as needed. Additionally, individuals with hypoparathyroidism may benefit from wearing a medical alert bracelet and receiving education on managing acute hypocalcemia.
In conclusion, hypoparathyroidism, or parathyroid hormone deficiency, is a condition characterized by inadequate production or secretion of PTH. It can cause various symptoms related to calcium imbalance. Treatment involves calcium and vitamin D supplementation, along with careful monitoring of calcium levels. If you suspect you may have hypoparathyroidism, it is important to consult with a healthcare professional for proper diagnosis and management.