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What are the best treatments for IgA nephropathy?

See the best treatments for IgA nephropathy here

IgA nephropathy treatments

Treatments for IgA Nephropathy


IgA nephropathy, also known as Berger's disease, is a kidney disorder characterized by the accumulation of immunoglobulin A (IgA) in the kidneys. This condition can lead to inflammation and damage to the kidney tissues, potentially causing kidney failure if left untreated. While there is no cure for IgA nephropathy, several treatments can help manage the symptoms, slow down the progression of the disease, and protect kidney function.



Dietary and Lifestyle Modifications


Dietary and lifestyle modifications play a crucial role in managing IgA nephropathy. These modifications aim to reduce the workload on the kidneys and minimize the risk of complications. Some key recommendations include:



  • Limiting salt intake to control blood pressure and fluid retention.

  • Reducing protein intake to alleviate the strain on the kidneys.

  • Avoiding excessive alcohol consumption to prevent further kidney damage.

  • Quitting smoking, as it can worsen kidney function and increase the risk of cardiovascular complications.

  • Maintaining a healthy weight through regular exercise and a balanced diet.



Blood Pressure Control


Blood pressure control is crucial in managing IgA nephropathy, as high blood pressure can further damage the kidneys. Medications called angiotensin-converting enzyme inhibitors (ACE inhibitors) or angiotensin receptor blockers (ARBs) are commonly prescribed to control blood pressure and reduce proteinuria (excessive protein in the urine). These medications also have a protective effect on the kidneys and can slow down the progression of the disease.



Immunosuppressive Therapy


In some cases, immunosuppressive therapy may be recommended to reduce inflammation and slow down the progression of IgA nephropathy. This treatment is typically reserved for individuals with more severe disease and persistent proteinuria. Immunosuppressive medications, such as corticosteroids, may be prescribed to suppress the immune system and reduce kidney inflammation. Other immunosuppressive agents, such as cyclophosphamide or mycophenolate mofetil, may also be used in certain cases.



Supportive Care


Supportive care is essential in managing IgA nephropathy and maintaining overall kidney health. Regular monitoring of kidney function through blood and urine tests is necessary to assess disease progression and adjust treatment accordingly. Additionally, managing other health conditions, such as diabetes or high cholesterol, is crucial to prevent further kidney damage. Close collaboration with healthcare professionals, including nephrologists and dietitians, is important to ensure comprehensive care and optimize treatment outcomes.



Research and Experimental Treatments


As IgA nephropathy is a complex and heterogeneous disease, ongoing research aims to identify new treatment options and improve patient outcomes. Experimental treatments, such as targeted therapies or novel immunosuppressive agents, are being investigated in clinical trials. These trials help evaluate the safety and efficacy of potential treatments and may offer new options for individuals with IgA nephropathy in the future.



Kidney Transplantation


In cases where IgA nephropathy progresses to end-stage renal disease (ESRD), kidney transplantation may be considered. This procedure involves replacing the damaged kidneys with a healthy kidney from a donor. Kidney transplantation can provide a long-term solution and significantly improve quality of life for individuals with ESRD. However, it is important to note that transplantation is not suitable for everyone, and careful evaluation by a transplant team is necessary to determine eligibility.



In conclusion, while there is no cure for IgA nephropathy, various treatments can help manage the symptoms, slow down disease progression, and protect kidney function. Dietary and lifestyle modifications, blood pressure control, immunosuppressive therapy, supportive care, and ongoing research play crucial roles in the management of this condition. In severe cases, kidney transplantation may be considered as a long-term solution. It is important for individuals with IgA nephropathy to work closely with healthcare professionals to develop a personalized treatment plan and optimize their overall kidney health.


Diseasemaps
2 answers
I am not completely sure what the best treatment is but there is a lot of research being done. I am currently in 3 different trials at Columbia Presbyterian Hospital. My treatments have been 12 rounds of 1000mg of soul-medrol infusions, high doses of prednisone pills, blood pressure medication and I tried cellcept which is an anti-rejection medication used by transplant recipients and donors. My body had an unusual reaction to the cellcept so I was only on it for a couple of days and had to stop.

Posted Mar 23, 2017 by Taylor 2795

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Stories of IgA nephropathy

IGA NEPHROPATHY STORIES
IgA nephropathy stories
This is a specialized kidney disease hospital in China founded in 1986. We treated different kinds of kidney disease including Iga by Traditional Chinese Medicine and has a satisfied effect.  Some Iga patients with kidney function damaged even impr...
IgA nephropathy stories
I have IGA, my kidney function is at 10%. I have a fistula in my arm and I'm going to start  dialysis soon.
IgA nephropathy stories
I have IGA and as a result I have TINU.    I have had this for almost  20 years.  I am at stage three moderate.  
IgA nephropathy stories
I was diagnosed in 2007 following a miscarriage. I was treated in 2008 after a decline in function.  I took pred cytoxan and bp meds. Due to a reaction from cytoxan i had liver failure in Aug of 2008. I was taken off cytoxan and revovered slowly fro...
IgA nephropathy stories
Diagnosed in April 2015 thru biopsy

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